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Mechanical forces drive degenerative spine disease through ROCK signalling Nat. Biomed. Eng. (IF 26.8) Pub Date : 2025-06-03
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Microfluidics combined with electron microscopy for rapid and high-throughput mapping of antibody–viral glycoprotein complexes Nat. Biomed. Eng. (IF 26.8) Pub Date : 2025-06-03
Leigh M. Sewall, Rebeca de Paiva Froes Rocha, Grace Gibson, Michelle Louie, Zhenfei Xie, Sandhya Bangaru, Andy S. Tran, Gabriel Ozorowski, Subhasis Mohanty, Nathan Beutler, Thomas F. Rogers, Dennis R. Burton, Albert C. Shaw, Facundo D. Batista, Blanca Chocarro Ruiz, Alba Torrents de la Peña, Andrew B. Ward -
NAD+ biosynthesis and mitochondrial repair in acute kidney injury via ultrasound-responsive thylakoid-integrating liposomes Nat. Biomed. Eng. (IF 26.8) Pub Date : 2025-06-03
Yao Lei, Yuzhu Wu, Wan-Ru Zhuang, Helin Zhao, Weidong Nie, Guanghao Wu, Dai-Wen Pang, Hai-Yan Xie -
A brain–computer interface working definition Nat. Biomed. Eng. (IF 26.8) Pub Date : 2025-06-02
Marc W. Slutzky, Mariska J. Vansteensel, Christian Herff, Robert A. GauntWe read with interest the Comment that suggests a taxonomy for brain–computer interfaces (BCIs) based on application1, and we agree that a nomenclature of different types of BCI may be useful for discussing this broad and expanding field comprised of stakeholders with different backgrounds and expertise, including groups new to BCI, such as media, investors and students. Nevertheless, we feel compelled
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Efficient and multiplexed somatic genome editing with Cas12a mice Nat. Biomed. Eng. (IF 26.8) Pub Date : 2025-05-30
Jess D. Hebert, Haiqing Xu, Yuning J. Tang, Paloma A. Ruiz, Colin R. Detrick, Jing Wang, Nicholas W. Hughes, Oscar Donosa, Vicky P. Siah, Laura Andrejka, Saswati Karmakar, Irenosen Aboiralor, Rui Tang, Rocio Sotillo, Julien Sage, Le Cong, Dmitri A. Petrov, Monte M. Winslow -
Ultrasensitive and long-lasting bioluminescence immunoassay for point-of-care viral antigen detection Nat. Biomed. Eng. (IF 26.8) Pub Date : 2025-05-30
Sungwan Kim, Giwon Cho, Jaebaek Lee, Khushi Doshi, Supriya Gharpure, Jisan Kim, Juyong Gwak, Joseph M. Hardie, Manoj K. Kanakasabapathy, Hemanth Kandula, Prudhvi Thirumalaraju, Younseong Song, Hui Chen, Daniel R. Kuritzkes, Jonathan Z. Li, Athe M. Tsibris, Hadi Shafiee -
Rapid clearance of achiral small-molecule drugs using de novo-designed proteins and their cyclic and mirror-image variants Nat. Biomed. Eng. (IF 26.8) Pub Date : 2025-05-29
Guilin Chen, Kai Zhao, Mengjiao Li, Yuefei Zhang, Tian Li, Jing Yuan, Lei Lu, Jesús Valdiviezo, Dan Liu, Nicholas F. Polizzi, William F. DeGrado, Bobo Dang -
ROCK-dependent mechanotransduction of macroscale forces drives fibrosis in degenerative spinal disease Nat. Biomed. Eng. (IF 26.8) Pub Date : 2025-05-29
Muhamed Hadzipasic, Margaret S. Sten, Elie Massaad, Ali Kiapour, Ian D. Connolly, Eric Esposito, Ryan Burns, George Nageeb, Muneeb A. Sharif, Joseph Bradley, Leland Richardson, Sami Shaikh, Bryan D. Choi, Gunnlaugur P. Nielsen, Jean-Valery C. Coumans, Lawrence F. Borges, John H. Shin, Alan J. Grodzinsky, Hadi T. Nia, Ganesh M. Shankar -
A wireless device for continuous measurement of brain parenchymal resistance tracks glymphatic function in humans Nat. Biomed. Eng. (IF 26.8) Pub Date : 2025-05-27
Paul Dagum, Laurent Giovangrandi, Swati Rane Levendovszky, Jake J. Winebaum, Tarandeep Singh, Yeilim Cho, Robert M. Kaplan, Michael S. Jaffee, Miranda M. Lim, Carla Vandeweerd, Jeffrey J. Iliff -
The cerebellum shapes motions by encoding motor frequencies with precision and cross-individual uniformity Nat. Biomed. Eng. (IF 26.8) Pub Date : 2025-05-27
Chia-Wei Liu, Yi-Mei Wang, Shun-Ying Chen, Liang-Yin Lu, Ting-Yu Liang, Ke-Chu Fang, Peng Chen, I-Chen Lee, Wen-Chuan Liu, Ami Kumar, Sheng-Han Kuo, Jye-Chang Lee, Chung-Chuan Lo, Shun-Chi Wu, Ming-Kai Pan -
Tension-induced directional migration of hepatic stellate cells potentially coordinates liver fibrosis progression Nat. Biomed. Eng. (IF 26.8) Pub Date : 2025-05-23
Lyu Zhou, Ziao Shi, Xuesi Yang, Jia’nan Zeng, Zhifeng You, Yuying Zhang, Zhiyue Zhu, Zhiqiang Liu, Yudi Niu, Hongsheng Yu, Jinliang He, Yi Long, Zhaozhao Wu, Yan Zhang, Cheng Lyu, Liping Deng, Yuan Wang, Congying Wu, Yanan Du -
A biochemical sensor with continuous extended stability in vivo Nat. Biomed. Eng. (IF 26.8) Pub Date : 2025-05-23
Yihang Chen, Kaiyu X. Fu, Renee Cotton, Zihao Ou, Jean Won Kwak, Jun-Chau Chien, Vladimir Kesler, Hnin Yin Yin Nyein, Michael Eisenstein, H. Tom Soh -
Long-term engraftment of human stem and progenitor cells for large-scale production of functional immune cells in engineered pigs Nat. Biomed. Eng. (IF 26.8) Pub Date : 2025-05-20
Zheng Hu, Jun Zou, Zhengzhu Wang, Kai Xu, Tang Hai, Sheng Zhang, Peipei An, Cong Fu, Shuai Dong, Yanan Lv, Jilong Ren, Zhiqiang Han, Chongyang Li, Jing Wang, Qingwei Wang, Renren Sun, Long Su, Hanjing Zuo, Qinghao Ding, Huimin Tian, Xinlan An, Yanhui Zhai, Dawei Yu, Chang Shu, Jin He, Liguang Sun, Tianmeng Sun, Xiangpeng Dai, Ziyi Li, Wei Li, Qi Zhou, Yong-Guang Yang -
High-throughput single-cell density measurements enable dynamic profiling of immune cell and drug response from patient samples Nat. Biomed. Eng. (IF 26.8) Pub Date : 2025-05-20
Weida Wu, Sarah H. Ishamuddin, Thomas W. Quinn, Smitha Yerrum, Ye Zhang, Lydie L. Debaize, Pei-Lun Kao, Sarah Marie Duquette, Mark A. Murakami, Morvarid Mohseni, Kin-Hoe Chow, Teemu P. Miettinen, Keith L. Ligon, Scott R. Manalis -
Treatment of a metabolic liver disease in mice with a transient prime editing approach Nat. Biomed. Eng. (IF 26.8) Pub Date : 2025-05-20
Tanja Rothgangl, András Tálas, Eleonora I. Ioannidi, Yanik Weber, Desirée Böck, Mai Matsushita, Elina Andrea Villiger, Lukas Schmidheini, Woohyun J. Moon, Paulo J. C. Lin, Steven H. Y. Fan, Kim F. Marquart, Cornelia Schwerdel, Nicole Rimann, Erica Faccin, Lukas Villiger, Hiromi Muramatsu, Máté Vadovics, Alessio Cremonesi, Péter István Kulcsár, Beat Thöny, Manfred Kopf, Johannes Häberle, Norbert Pardi -
Activating membrane receptors with ultrasound Nat. Biomed. Eng. (IF 26.8) Pub Date : 2025-05-16
Yi-Xian Qin, Elias Georgas -
siRNA conjugate with high albumin affinity and degradation resistance for delivery and treatment of arthritis in mice and guinea pigs Nat. Biomed. Eng. (IF 26.8) Pub Date : 2025-05-16
Juan M. Colazo, Megan C. Keech, Veeraj Shah, Ella N. Hoogenboezem, Justin H. Lo, Nora Francini, Nina T. Cassidy, Fang Yu, Alexander G. Sorets, Joshua T. McCune, Carlisle R. DeJulius, Hongsik Cho, Danielle L. Michell, Tristan Maerz, Kacey C. Vickers, Katherine N. Gibson-Corley, Karen A. Hasty, Leslie J. Crofford, Rebecca S. Cook, Craig L. Duvall -
A compact, wireless system for continuous monitoring of breast milk expressed during breastfeeding Nat. Biomed. Eng. (IF 26.8) Pub Date : 2025-05-14
Jihye Kim, Seyong Oh, Raudel Avila, Hee-Sup Shin, Matthew Banet, Jennifer Wicks, Anthony R. Banks, Yonggang Huang, Jae-Young Yoo, Daniel T. Robinson, Craig F. Garfield, John A. Rogers -
Multiplex imaging of amyloid-β plaques dynamics in living brains with quinoline-malononitrile-based probes Nat. Biomed. Eng. (IF 26.8) Pub Date : 2025-05-13
Jianfeng Dai, Weijun Wei, Chenxu Yan, Ding-Kun Ji, Caiqi Liu, Jialiang Huang, Chenyi Liang, Jianjun Liu, Zhiqian Guo, Wei-Hong Zhu -
Focused ultrasound-microbubble treatment arrests the growth and formation of cerebral cavernous malformations Nat. Biomed. Eng. (IF 26.8) Pub Date : 2025-05-13
Delaney G. Fisher, Tanya Cruz, Matthew R. Hoch, Khadijeh A. Sharifi, Ishaan M. Shah, Catherine M. Gorick, Victoria R. Breza, Anna C. Debski, Joshua D. Samuels, Jason P. Sheehan, David Schlesinger, David Moore, James W. Mandell, John R. Lukens, G. Wilson Miller, Petr Tvrdik, Richard J. Price -
Targeting inflammation with chimeric antigen receptor macrophages using a signal switch Nat. Biomed. Eng. (IF 26.8) Pub Date : 2025-05-07
Qi Cao, Yiping Wang, Jianwei Chen, Ruifeng Wang, Titi Chen, Brian Gloss, Scott A. Read, Xuerong Wang, Vincent W. S. Lee, Leighton Clancy, Natasha M. Rogers, Stephen I. Alexander, Guoping Zheng, Di Yu, David C. H. Harris -
Antimicrobial peptides boosted by ultrasound Nat. Biomed. Eng. (IF 26.8) Pub Date : 2025-05-02
Soraia Fernandes, Francesca Cavalieri -
Enhanced nanoparticle delivery across vascular basement membranes of tumours using nitric oxide Nat. Biomed. Eng. (IF 26.8) Pub Date : 2025-05-02
Wei Jiang, Zixuan Guo, Qin Wang, Ziqi Chen, Wang Dong, Qirui Liang, Yinghong Hao, Huimin Pan, Cici Zeng, Hang Liu, Yucai Wang -
A sonosensitive diphenylalanine-based broad-spectrum antimicrobial peptide Nat. Biomed. Eng. (IF 26.8) Pub Date : 2025-05-02
Xiaoguang Zhang, Xiaobo Feng, Liang Ma, Jie Lei, Gaocai Li, Weifeng Zhang, Huaizhen Liang, Bide Tong, Di Wu, Cao Yang, Lei Tan -
Magnetically driven biohybrid blood hydrogel fibres for personalized intracranial tumour therapy under fluoroscopic tracking Nat. Biomed. Eng. (IF 26.8) Pub Date : 2025-05-01
Ben Wang, Jie Shen, Chenyang Huang, Zhicheng Ye, Jiajun He, Xinyu Wu, Zhiguang Guo, Li Zhang, Tiantian Xu -
A live bacteria enzyme assay for identification of human disease mutations and drug screening Nat. Biomed. Eng. (IF 26.8) Pub Date : 2025-04-30
Donghui Choe, Bernhard O. Palsson -
A highly mobile adeno-associated virus targeting vascular smooth muscle cells for the treatment of pulmonary arterial hypertension Nat. Biomed. Eng. (IF 26.8) Pub Date : 2025-04-29
Yoojin Kim, Yeongju Yeo, Minju Kim, Yong-Wook Son, Joowon Kim, Koung Li Kim, Seohee Kim, Seokmin Oh, Yunha Kim, Hyowoo Lee, Hyun-Woo Park, Dongsoo Lee, Sung Jin Lee, Changmin Kang, Hongyoung Choi, Chan Soon Park, Seung-Pyo Lee, Wonhee Suh, Jae-Hyung Jang -
High-resolution prosthetic hearing with a soft auditory brainstem implant in macaques Nat. Biomed. Eng. (IF 26.8) Pub Date : 2025-04-18
Alix Trouillet, Emilie Revol, Florent-Valéry Coen, Florian Fallegger, Aurélie Chanthany, Maude Delacombaz, Laurine Kolly, Ivan Furfaro, Florian Lanz, Vivek Kanumuri, Victor Adenis, Alejandro Garcia-Chavez, M. Christian Brown, Lukas Anschuetz, Jocelyne Bloch, Daniel J. Lee, Stéphanie P. Lacour -
Author Correction: Viscoelastic synthetic antigen-presenting cells for augmenting the potency of cancer therapies Nat. Biomed. Eng. (IF 26.8) Pub Date : 2025-04-15
Zeyang Liu, Yan-Ruide Li, Youcheng Yang, Yu Zhu, Weihao Yuan, Tyler Hoffman, Yifan Wu, Enbo Zhu, Jana Zarubova, Jun Shen, Haochen Nan, Kun-Wei Yeh, Mohammad Mahdi Hasani-Sadrabadi, Yichen Zhu, Ying Fang, Xinyang Ge, Zhizhong Li, Jennifer Soto, Tzung Hsiai, Lili Yang, Song Li -
Water and ions binding to extracellular matrix drives stress relaxation, aiding MRI detection of swelling-associated pathology Nat. Biomed. Eng. (IF 26.8) Pub Date : 2025-04-15
Matthias R. Kollert, Martin Krämer, Nicholas M. Brisson, Victoria Schemenz, Serafeim Tsitsilonis, Taimoor H. Qazi, Peter Fratzl, Viola Vogel, Jürgen R. Reichenbach, Georg N. Duda -
An implantable hydrogel-based phononic crystal for continuous and wireless monitoring of internal tissue strains Nat. Biomed. Eng. (IF 26.8) Pub Date : 2025-04-14
Ye Tian, Yueying Yang, Hanchuan Tang, Jiaxin Wang, Na Li, Yifan Cheng, Tianyu Kang, Jiarui Tang, Mengyuan Zhou, Wei Chen, Yan Yu, Xinqi Liu, Xurui Liu, Liqun Xu, Zhouping Yin, Jianfeng Zang -
In vivo generation of tolerogenic APCs using PDL1 mRNA-loaded nanoparticles Nat. Biomed. Eng. (IF 26.8) Pub Date : 2025-04-09
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Author Correction: Organ-specific metastases obtained by culturing colorectal cancer cells on tissue-specific decellularized scaffolds Nat. Biomed. Eng. (IF 26.8) Pub Date : 2025-04-09
Xi Tian, Michael E. Werner, Kyle C. Roche, Ariel D. Hanson, Henry P. Foote, Stephanie K. Yu, Samuel B. Warner, Jonathan A. Copp, Haydee Lara, Eliane L. Wauthier, Joseph M. Caster, Laura E. Herring, Longzhen Zhang, Joel E. Tepper, David S. Hsu, Tian Zhang, Lola M. Reid, Andrew Z. WangCorrection to: Nature Biomedical Engineering https://doi.org/10.1038/s41551-018-0231-0, published online 23 April 2018.
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Site-directed antibody conjugation via ubiquitination Nat. Biomed. Eng. (IF 26.8) Pub Date : 2025-04-09
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Site-directed multivalent conjugation of antibodies to ubiquitinated payloads Nat. Biomed. Eng. (IF 26.8) Pub Date : 2025-04-09
Angela F. el Hebieshy, Zacharias Wijfjes, Camille M. Le Gall, Jim Middelburg, Kim E. de Roode, Felix L. Fennemann, Marjolein Sluijter, Thorbald van Hall, Douwe J. Dijkstra, Leendert A. Trouw, Floris J. van Dalen, Andrea Rodgers Furones, Johan M. S. van der Schoot, Ian Derksen, Hans de Haard, Bas van der Woning, Cami M. P. Talavera Ormeño, Bjorn R. van Doodewaerd, Carl G. Figdor, Gerbrand J. van der -
Synthetic data boosts medical foundation models Nat. Biomed. Eng. (IF 26.8) Pub Date : 2025-04-08
Bin Sheng, Pearse A. Keane, Yih-Chung Tham, Tien Yin Wong -
Coordinated AI agents for advancing healthcare Nat. Biomed. Eng. (IF 26.8) Pub Date : 2025-04-01
Michael Moritz, Eric Topol, Pranav Rajpurkar -
Generation of tolerogenic antigen-presenting cells in vivo via the delivery of mRNA encoding PDL1 within lipid nanoparticles Nat. Biomed. Eng. (IF 26.8) Pub Date : 2025-03-28
Yang Liu, Qian Liu, Baowen Zhang, Shanshan Chen, Yanqiong Shen, Zhibin Li, Jiachen Zhang, Yi Yang, Min Li, Yucai Wang -
Osteopontin attenuates the foreign-body response to silicone implants Nat. Biomed. Eng. (IF 26.8) Pub Date : 2025-03-24
Michelle F. Griffin, Jennifer B. Parker, Ruth Tevlin, Norah E. Liang, Caleb Valencia, Annah Morgan, Maxwell Kuhnert, Mauricio Downer, Emily L. Meany, Jason L. Guo, Dominic Henn, Renato S. Navarro, Kerry Shefren, Dung Nguyen, Geoffrey C. Gurtner, Sarah C. Heilshorn, Charles K. F. Chan, Michael Januszyk, Eric A. Appel, Arash Momeni, Derrick C. Wan, Michael T. Longaker -
Cas12a-knock-in mice for multiplexed genome editing, disease modelling and immune-cell engineering Nat. Biomed. Eng. (IF 26.8) Pub Date : 2025-03-20
Kaiyuan Tang, Liqun Zhou, Xiaolong Tian, Shao-Yu Fang, Erica Vandenbulcke, Andrew Du, Johanna Shen, Hanbing Cao, Jerry Zhou, Krista Chen, Hyunu R. Kim, Zhicheng Luo, Shan Xin, Shawn H. Lin, Daniel Park, Luojia Yang, Yueqi Zhang, Kazushi Suzuki, Medha Majety, Xinyu Ling, Stanley Z. Lam, Ryan D. Chow, Ping Ren, Bo Tao, Keyi Li, Adan Codina, Xiaoyun Dai, Xingbo Shang, Suxia Bai, Timothy Nottoli, Andre -
Non-viral intron knock-ins for targeted gene integration into human T cells and for T-cell selection Nat. Biomed. Eng. (IF 26.8) Pub Date : 2025-03-07
Theodore L. Roth, Johnathan Lu, Alison McClellan, Courtney Kernick, Oliver Takacsi-Nagy, Ansuman T. Satpathy -
A deep-learning model for quantifying circulating tumour DNA from the density distribution of DNA-fragment lengths Nat. Biomed. Eng. (IF 26.8) Pub Date : 2025-03-07
Guanhua Zhu, Chowdhury Rafeed Rahman, Victor Getty, Denis Odinokov, Probhonjon Baruah, Hanaé Carrié, Avril Joy Lim, Yu Amanda Guo, Zhong Wee Poh, Ngak Leng Sim, Ahmed Abdelmoneim, Yutong Cai, Lakshmi Narayanan Lakshmanan, Danliang Ho, Saranya Thangaraju, Polly Poon, Yi Ting Lau, Anna Gan, Sarah Ng, Si-Lin Koo, Dawn Q. Chong, Brenda Tay, Tira J. Tan, Yoon Sim Yap, Aik Yong Chok, Matthew Chau Hsien Ng -
Identifying perturbations that boost T-cell infiltration into tumours via counterfactual learning of their spatial proteomic profiles Nat. Biomed. Eng. (IF 26.8) Pub Date : 2025-03-05
Zitong Jerry Wang, Abdullah S. Farooq, Yu-Jen Chen, Aman Bhargava, Alexander M. Xu, Matt W. Thomson -
A positron emission tomography tracer for the imaging of oxidative stress in the central nervous system Nat. Biomed. Eng. (IF 26.8) Pub Date : 2025-03-05
Justin H. Wilde, Yu-Yo Sun, Spenser R. Simpson, Ethan R. Hill, Zhongxiao Fu, Emily J. Bian, Melissa M. Kinkaid, Paulina Villanueva, Aden F. Weybright, William R. Terrell, Zoraiz Qureshi, Shashika S. Perera, Heather S. Sheppard, James R. Stone, Bijoy K. Kundu, Chia-Yi Kuan, Kiel D. Neumann -
A data-efficient strategy for building high-performing medical foundation models Nat. Biomed. Eng. (IF 26.8) Pub Date : 2025-03-05
Yuqi Sun, Weimin Tan, Zhuoyao Gu, Ruian He, Siyuan Chen, Miao Pang, Bo Yan -
Deep mutational learning for the selection of therapeutic antibodies resistant to the evolution of Omicron variants of SARS-CoV-2 Nat. Biomed. Eng. (IF 26.8) Pub Date : 2025-03-05
Lester Frei, Beichen Gao, Jiami Han, Joseph M. Taft, Edward B. Irvine, Cédric R. Weber, Rachita K. Kumar, Benedikt N. Eisinger, Andrey Ignatov, Zhouya Yang, Sai T. Reddy -
3D-printed perfused models of the penis for the study of penile physiology and for restoring erectile function in rabbits and pigs Nat. Biomed. Eng. (IF 26.8) Pub Date : 2025-03-04
Zhenxing Wang, Xuemin Liu, Tan Ye, Zhichen Zhai, Kai Wu, Yudi Kuang, Serge Ostrovidov, Dan Shao, Yingjun Wang, Kam W. Leong, Xuetao Shi -
Radioprotection of healthy tissue via nanoparticle-delivered mRNA encoding for a damage-suppressor protein found in tardigrades Nat. Biomed. Eng. (IF 26.8) Pub Date : 2025-02-26
Ameya R. Kirtane, Jianling Bi, Netra U. Rajesh, Chaoyang Tang, Miguel Jimenez, Emily Witt, Megan K. McGovern, Arielle B. Cafi, Samual J. Hatfield, Lauren Rosenstock, Sarah L. Becker, Nicole Machado, Veena Venkatachalam, Dylan Freitas, Xisha Huang, Alvin Chan, Aaron Lopes, Hyunjoon Kim, Nayoon Kim, Joy E. Collins, Michelle E. Howard, Srija Manchkanti, Theodore S. Hong, James D. Byrne, Giovanni Traverso -
Enhancing phage therapy by coating single bacteriophage-infected bacteria with polymer to preserve phage vitality Nat. Biomed. Eng. (IF 26.8) Pub Date : 2025-02-25
Sisi Lin, Guocheng Xie, Jun He, Lu Meng, Yan Pang, Jinyao Liu -
Molecular probes for in vivo optical imaging of immune cells Nat. Biomed. Eng. (IF 26.8) Pub Date : 2025-02-21
Jing Liu, Penghui Cheng, Cheng Xu, Kanyi Pu -
Characterization of tumour heterogeneity through segmentation-free representation learning on multiplexed imaging data Nat. Biomed. Eng. (IF 26.8) Pub Date : 2025-02-20
Jimin Tan, Hortense Le, Jiehui Deng, Yingzhuo Liu, Yuan Hao, Michelle Hollenberg, Wenke Liu, Joshua M. Wang, Bo Xia, Sitharam Ramaswami, Valeria Mezzano, Cynthia Loomis, Nina Murrell, Andre L. Moreira, Kyunghyun Cho, Harvey I. Pass, Kwok-Kin Wong, Yi Ban, Benjamin G. Neel, Aristotelis Tsirigos, David Fenyö -
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Nitroglycerin-responsive gene switch for the on-demand production of therapeutic proteins Nat. Biomed. Eng. (IF 26.8) Pub Date : 2025-02-14
Mohamed Mahameed, Shuai Xue, Benjamin Danuser, Ghislaine Charpin-El Hamri, Mingqi Xie, Martin Fussenegger -
Microfluidic technologies for enhancing the potency, predictability and affordability of adoptive cell therapies Nat. Biomed. Eng. (IF 26.8) Pub Date : 2025-02-14
Zongjie Wang, Shana O. Kelley -
Targeting vaccines to dendritic cells by mimicking the processing and presentation of antigens in xenotransplant rejection Nat. Biomed. Eng. (IF 26.8) Pub Date : 2025-02-13
Jinjin Wang, Yuxuan Zhang, Yaru Jia, Haonan Xing, Fengfei Xu, Bozhang Xia, Wenjia Lai, Yuan Yuan, Xianlei Li, Shaobo Shan, Junge Chen, Weisheng Guo, Jinchao Zhang, Aiping Zheng, Jinghong Li, Ningqiang Gong, Xing-Jie Liang -
High-throughput multiplexed serology via the mass-spectrometric analysis of isotopically barcoded beads Nat. Biomed. Eng. (IF 26.8) Pub Date : 2025-02-12
Alexandros P. Drainas, David R. McIlwain, Alec Dallas, Theresa Chu, Antonio Delgado-González, Maya Baron, Maria Angulo-Ibáñez, Angelica Trejo, Yunhao Bai, John W. Hickey, Guolan Lu, Scott Lu, Jesus Pineda-Ramirez, Khamal Anglin, Eugene T. Richardson, John C. Prostko, Edwin Frias, Venice Servellita, Noah Brazer, Charles Y. Chiu, Michael J. Peluso, Jeffrey N. Martin, Oliver F. Wirz, Tho D. Pham, Scott -
A gut-on-a-chip incorporating human faecal samples and peristalsis predicts responses to immune checkpoint inhibitors for melanoma Nat. Biomed. Eng. (IF 26.8) Pub Date : 2025-02-12
Mattia Ballerini, Serena Galiè, Punit Tyagi, Carlotta Catozzi, Hariam Raji, Amir Nabinejad, Angeli D. G. Macandog, Alessandro Cordiale, Bianca Ionela Slivinschi, Karol K. Kugiejko, Martina Freisa, Paola Occhetta, Jennifer A. Wargo, Pier F. Ferrucci, Emilia Cocorocchio, Nicola Segata, Andrea Vignati, Andrey Morgun, Michela Deleidi, Teresa Manzo, Marco Rasponi, Luigi Nezi -
Synaptic connectivity mapping among thousands of neurons via parallelized intracellular recording with a microhole electrode array Nat. Biomed. Eng. (IF 26.8) Pub Date : 2025-02-11
Jun Wang, Woo-Bin Jung, Rona S. Gertner, Hongkun Park, Donhee Ham -
Small circular RNAs as vaccines for cancer immunotherapy Nat. Biomed. Eng. (IF 26.8) Pub Date : 2025-02-07
Yu Zhang, Xiang Liu, Tingting Shen, Qiyan Wang, Shurong Zhou, Suling Yang, Shimiao Liao, Ting Su, Lei Mei, Bei Zhang, Khoa Huynh, Linying Xie, Youzhong Guo, Chunqing Guo, Katarzyna M. Tyc, Xufeng Qu, Xiang-Yang Wang, Jinze Liu, Guizhi Zhu -
Author Correction: Restoration of tumour-growth suppression in vivo via systemic nanoparticle-mediated delivery of PTENmRNA Nat. Biomed. Eng. (IF 26.8) Pub Date : 2025-02-05
Mohammad Ariful Islam, Yingjie Xu, Wei Tao, Jessalyn M. Ubellacker, Michael Lim, Daniel Aum, Gha Young Lee, Kun Zhou, Harshal Zope, Mikyung Yu, Wuji Cao, James Trevor Oswald, Meshkat Dinarvand, Morteza Mahmoudi, Robert Langer, Philip W. Kantoff, Omid C. Farokhzad, Bruce R. Zetter, Jinjun Shi