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Oxr1 and Ncoa7 regulate V-ATPase to achieve optimal pH for glycosylation within the Golgi apparatus and trans-Golgi network
Proceedings of the National Academy of Sciences of the United States of America ( IF 9.4 ) Pub Date : 2025-05-30 , DOI: 10.1073/pnas.2505975122
Shin-ichiro YoshimuraTomoaki SobajimaMasataka KuniiAkihiro HaradaaDepartment of Cell Biology, Graduate School of Medicine, The University of Osaka, Suita 565-0871, Osaka, Japan

Proceedings of the National Academy of Sciences, Volume 122, Issue 22, June 2025.
SignificanceIn the secretory pathway, the pH within organelles is gradually acidified, starting at 7.1 to 7.2 in the endoplasmic reticulum, decreasing to 6.0 to 6.7 in the Golgi apparatus/trans-Golgi network (Golgi/TGN), and reaching 4.5 to 5.0 in ...


中文翻译:

Oxr1 和 Ncoa7 调节 V-ATP 酶,以达到高尔基体和反式高尔基体网络内糖基化的最佳 pH 值

美国国家科学院院刊,第 122 卷,第 22 期,2025 年 6 月。
意义在分泌途径中,细胞器内的 pH 值逐渐酸化,从内质网的 7.1 至 7.2 开始,在高尔基体/反式高尔基体网络 (Golgi/TGN) 中降至 6.0 至 6.7,并在 ...
更新日期:2025-06-04
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