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Powering new therapeutics with precision mitochondrial editing
Nature Biotechnology ( IF 33.1 ) Pub Date : 2025-06-03 , DOI: 10.1038/s41587-025-02693-x


More precise base editors make mitochondrial DNA editing efficient enough to model disease and correct pathogenic mutations in rodents, but they are slow to move into clinical trials.

中文翻译:

通过精确的线粒体编辑为新疗法提供动力

更精确的碱基编辑器使线粒体 DNA 编辑足够高效,可以模拟疾病并纠正啮齿动物的致病性突变,但它们进入临床试验的速度很慢。
更新日期:2025-06-03
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