1 Introduction Doctoral education in nursing typically includes training in research methodologies, methods, human research ethics, data analysis, and knowledge translation (KT), but minimal education on character development. What is known, however, is that a researcher's capability to understand the perspectives of knowledge users (i.e., patients, parents, clinicians, health system leaders, policy-makers

This study explores the lived experiences of critical care nurses who are also mothers, focusing on their challenges with breastfeeding and pumping at work.

A recent study examining the relationship between daily activity levels and elder abuse and neglect in Turkey offers critical insights into the complexities of maltreatment among older adults (Bülbül Maraş and Ünlübaş 2025). The research demonstrated that factors such as lower education, poor self-rated health, intrafamily conflict and regional variation were significantly associated with increased

Health-promoting lifestyle (HPL) is strongly associated with health outcomes. In clinical practice, health-promotion behaviours in patients with head and neck cancer (HNC) are not good, which seriously affects patients' prognosis. This study aims to investigate the current status and influencing factors of HPL in HNC patients.

To systematically review published studies on fall risk prediction models for inpatients.

Targeted next-generation sequencing (tNGS) has emerged as an advanced diagnostic technique. While tNGS is increasingly recognized as a valuable tool for detecting infections, its most relevant clinical indications remain underdefined. This study aimed to evaluate the clinical utility of tNGS for lower respiratory tract infections (LRTIs). We conducted a prospective, observational study to evaluate

The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock (J-SSCG) 2020 aimed to standardize sepsis care in Japan. However, the extent of their impact on clinical practice remains uncertain. We conducted a nationwide retrospective cohort study using the Japanese Diagnosis Procedure Combination database between April 2018 and December 2021. Of the 118 clinical questions (CQs)

Non-invasive ventilation (NIV) is widely used in emergency settings for acute respiratory failure, with NIV failure, usually defined by the need for tracheal intubation, as its primary complication. In emergency settings where patients may not be intubated or or where NIV represents the ceiling of care, a pragmatic understanding of NIV failure requires a broader definition that incorporates early clinical

Low skeletal mass, often present at hospital admission, has been associated with poor prognoses. To explore the association between computed tomography (CT)-derived skeletal muscle mass at the lumbar level and short- and long-term mortality in critically ill patients. Following PRISMA 2020 guidelines, we included studies on critically ill adults (≥ 18 years) hospitalized in intensive care units (ICU)

The perspective by Ji et al. [1] provides a timely synthesis of evidence for traditional Chinese medicine (TCM) in sepsis management and underscores critical challenges in clinical translation. While the authors comprehensively outline the methodological limitations of existing TCM trials and emphasize the need for high-quality evidence, three interrelated issues warrant further discussion to guide

In Critical Care, Mellado-Artigas and colleagues [1] aimed to evaluate the effect of initiating invasive mechanical ventilation (IMV) immediately versus waiting in patients with hypoxemic respiratory failure on one-year mortality. They used the target trial emulation framework, which is an increasingly recognized approach for designing observational studies that aim to compare treatment strategies

The recruitment-to-inflation (R/I) ratio is a new bedside tool with potential to evaluate lung recruitability by positive end-expiratory pressure (PEEP) but was only validated using pressure–volume curves and the optimal threshold separating low and high recruiters by PEEP is not precisely known. The aim of the study is to evaluate the diagnostic performance of the R/I ratio using computed tomography

AimTo combine the Job Demand‐Resource (JD‐R) model with machine learning (ML) techniques to identify the key factors affecting job burnout (JB) among Chinese nurses.DesignA Cross‐Sectional Study.MethodsThis study utilised a stratified sampling method to recruit 3449 eligible nurses from eight cities in Shandong Province between June and December 2021. After data cleaning, 2998 valid samples were retained

BackgroundThe nursing workforce is central to healthcare delivery, yet racial and ethnic disparities persist. Systemic barriers such as implicit bias, institutional racism, and socioeconomic obstacles hinder the career progression of underrepresented nurses. Addressing these disparities is critical to fostering a diverse workforce that can effectively meet the needs of diverse patient populations.AimThis

AimPositive aspects of caregiving among family carers of persons living with dementia not only benefit the carers' health, but also enhance the quality and sustainability of invaluable informal care resources. To better inform the development of carer support intervention to optimise positive aspects of caregiving, this paper tested the integrative theoretical model based on stress coping and meaning‐making

AimTo explore the lived experience of young people aged 16–24 years diagnosed with melanoma and that of their significant other in England.DesignInterpretive phenomenological analysis.MethodsData were collected between August 2023 and January 2024 from one specialist cancer centre in England. Thirteen young people were approached, and 10 took part. Each young person was asked to nominate a significant

AimTo measure patients' views of nurses' communication and interpersonal skills during acute hospitalisation.DesignThis was a descriptive cross‐sectional study.MethodsFrom January to June 2024, a convenience sampling approach was used to recruit patients hospitalised in acute care wards across two healthcare organisations in regional Victoria, Australia. A self‐report survey, the Communication Assessment

Cerebral compliance describes the pressure–volume relationship within the intracranial space, quantifying the brain’s capacity to accommodate changes in volume before significant increases in intracranial pressure (ICP) occur. The pulse shape index – PSI—classifies the ICP pulse-wave-configuration into 4 categories representing the incremental state of compliance. In this analysis we explore the metric

This study assessed the accuracy of three International Classification of Diseases (ICD) codes methods derived from Global Burden of Disease (GBD) sepsis study (modified GBD method) in identifying sepsis, compared to the Angus method. Sources of errors in these methods were also reported. Prospective multicentre, observational, study. Emergency Department patients aged ≥ 16 years with high sepsis risk

It was a pleasure to read the recent publication in Critical Care on the cardiovascular effects of lactate [1]. The authors conducted a randomized comparison between the infusion of hypertonic lactated solution and hypertonic saline solution and their effects on echocardiography measurements. The authors equalized the osmolarity of the solutions to ensure that there were no differences in volume expansion

AimThis study aims to explore occupational burnout among Chinese nurses from two perspectives: first, by comparing changes in emotional exhaustion, depersonalisation and personal accomplishment before and after the COVID‐19 pandemic; and second, by identifying long‐term work‐related stressors and structural factors contributing to burnout.DesignA mixed‐methods approach was adopted, combining a systematic

AimTo describe and compare attitudes toward hand hygiene and the perceived effectiveness of prevention methods among nursing students and registered nurses at a university and its affiliated university hospital.DesignA descriptive cross‐sectional comparative survey.MethodsA total of 201 first‐ and final‐semester nursing students and registered nurses completed the World Health Organisation's ‘Perceptions

AimTo explore the relationship between sleep and cognitive frailty in older adults.DesignA systematic review and meta‐analysis.Data SourcesThe Web of Science, Cochrane Library, CINAHL, Embase, PsycINFO and PubMed databases were searched from inception to October 28, 2024.MethodsTwo investigators independently conducted literature screening, data extraction and quality assessment. The Joanna Briggs

AimTo evaluate the acceptability and safety of a fluid volume assessment tool integrating clinical signs, patient‐reported symptoms and bioimpedance analysis as a clinical decision aid in haemodialysis.DesignSingle‐centre, 6‐month clinical implementation feasibility pilot study.MethodsA convenience sample of 50 healthcare staff and 50 hospitalised haemodialysis patients was recruited. The intervention

Fluid management is an essential component of renal replacement therapy (RRT) in critically ill patients. Both a positive cumulative fluid balance (CFB) and a high net ultrafiltration (NUF) rate have been reported to be associated with adverse outcomes in epidemiological studies, although the overall trajectory of fluid balance after RRT initiation is not well-described. We aimed to characterize trajectories

AimTo present the current evidence on the nature and principles of Equity, Diversity and Inclusion (EDI) in Nursing Education Institutions (NEIs).MethodFive databases (CINAHL, Medline, Scopus, ERIC and Educational Research Complete) and websites of Canadian nursing education institutions were searched for studies and grey literature on EDI. Information was analysed using the Diversio Diversity and

AimsTo explore parents’ experiences of parenting adolescents with food allergies.DesignAn interpretive descriptive qualitative study.MethodsSemi‐structured interviews were conducted between November 2023 and March 2024 with 11 parents of adolescents with food allergies aged 12–16 years, 8 mothers and 3 fathers. Reflexive thematic analysis was conducted.ResultsThree themes were generated: (1) Impact

AimThe aim of this study was to examine the perceptions and experiences of emergency nurses managing acute pain in critically ill patients.DesignQualitative descriptive study.MethodNon‐participant observations (n = 46, 157 h across 10 shifts) and semi‐structured interviews (n = 30) were conducted at two Australian metropolitan emergency departments from November to December 2020. Transcribed data were

AimTo describe the organisation of nurse‐led clinics and the factors facilitating or hindering their implementation based on experiences in five countries.DesignDescriptive multimethod study.MethodsWe analysed policy documents, nursing competency profiles and scientific literature and conducted 27 semi‐structured interviews with stakeholders from the Netherlands, Ontario, Ireland, France and Finland

AimTo adapt and validate the Behavioural Indicators of Pain Scale (ESCID) for use in critically ill patients with acquired brain injury and artificial airway who are unable to self‐report (ESCID‐DC).DesignMulticentre, prospective, observational validation study of the Behavioural Indicators of Pain Scale‐Brain Injury (ESCID‐DC).MethodsThe study will be carried out in three phases, as follows: (1) Content

Astrocytes assist in modulating the breathing cycle. Mechanically ventilated sedated patients have their respiratory drive suppressed, which may affect astrocytes’ function. This pilot study showed that phrenic nerve stimulation may protect astrocyte function and activity, maintaining the integrity of the blood–brain barrier in these patients. Neural control of respiratory rhythm is a complicated process

The optimal time for initiating kidney replacement therapy (KRT) in acute kidney injury (AKI) has been extensively studied in recent years. In contrast, there are currently insufficient data on the best time to discontinue KRT. One diagnostic option to unmask tubular reserve and indirectly estimate the glomerular filtration rate is the furosemide stress test (FST). We conducted a prospective, observational

Renal replacement therapy (RRT) is commonly used in critically ill patients with acute kidney injury (AKI). However, optimal timing of RRT liberation remains controversy. This meta-analysis evaluates novel biomarkers to predict successful RRT liberation in critically ill AKI patients. The systematic review reported following PRISMA guidelines, PubMed, Embase, and Scopus were searched up to May 2, 2025

Major Adverse Kidney Events within 30 days (MAKE30) is an important patient-centered outcome for assessing the impact of acute kidney injury (AKI). Existing prediction models for MAKE30 are static and overlook dynamic changes in clinical status. We introduce ORAKLE, a novel deep-learning model that utilizes evolving time-series data to predict MAKE30, enabling personalized, patient-centered approaches

Computed tomography perfusion (CTP) of the brain, are increasingly being employed for the assessment of critically ill patients admitted to intensive care units (ICU), including comatose cardiac arrest patients (CCAP). The purpose of our study was to validate the use of CTP in predicting in-hospital mortality in CCAPs. This prospective cohort study enrolled newly admitted adult CCAP, with an out of

Aim(s)To explore how practical nurses perceive telehomecare in relation to sustainability.DesignThis study had a qualitative exploratory design.MethodsTen practical nurses working with telehomecare were interviewed in February–April 2024. The interviews were individual, semi‐structured and were analysed through Braun and Clarke's reflexive thematic analysis.ResultsThe overarching theme of this study

One-way speaking valves (OWV) can be used in tracheostomy patients. Their design enables inhalation via the tracheostomy tube due to an open diaphragm, that closes immediately before or during exhalation, thus restoring normal physiological exhalation pathways. This mechanism provides multiple physiological and psychological benefits, including enabling voice, re-establishes subglottic pressure, enhances

We were highly interested in reading the clinical research conducted by Kim et al. [1]. This study is a single-center, retrospective clinical cohort investigation with a large sample size, focusing primarily on the significance of lower respiratory tract (LRT) cytomegalovirus (CMV) positivity in the prognosis of critically ill patients. The research departs from the traditional focus on CMV reactivation

AimsNurse migration remains a significant issue in global healthcare, often driven by economic incentives, work environment factors, and professional development opportunities. Greece's prolonged economic crisis and low nurse‐to‐population ratios have further intensified the outflow of skilled nursing personnel. We aimed to examine how demographic, educational, and professional factors, along with

AimTo assess the feasibility and acceptability of a group‐based intervention for addressing fear of childbirth in multiparous women.DesignSingle‐arm non‐randomised feasibility trial with a convergent mixed methods design.MethodsThe intervention, conducted at a central maternity hospital and led by a psychiatric nurse and a midwife, included three prenatal and one postnatal face‐to‐face group sessions

BackgroundSymptom networks offer a new approach to explore the relationships among various symptoms and provide information for optimising precise symptom management strategies. However, no previous studies have identified the central symptoms of multidimensional frailty.DesignA cross‐sectional study was conducted from December 2023 to March 2024 in China.Settings and ParticipantsA total of 933 community‐dwelling

The frequency of micturition serves as an important indicator in assessing lower urinary tract function and overall urinary health (Kakde et al. 2018; Nikseresht et al. 2015). Recent research by He et al. (He et al. 2025) has emphasised an important psychosocial aspect linked to frequent urination–stigma. Their study revealed that individuals who urinate frequently face embarrassment, social withdrawal

AimTo explore the experiences of and reasons for midwives leaving practice.DesignA qualitative approach applying a social constructivism interpretative framework.MethodsTwenty participants were selected for interviews based on reasons for leaving midwifery practice between October 2022 and April 2023. Thematic analysis was used to identify themes, and results were checked for trustworthiness through

AimsTo identify latent profiles of insomnia, fatigue, recovery, psychological distress and burnout among hospital nurses; examine variations in personal and work‐related characteristics across profiles; investigate associations between profiles and outcomes such as patient care quality, nursing work satisfaction and workplace satisfaction; and assess the moderating role of organisational support on

1 Introduction Over the past 50 years, there have been significant and widespread reforms to mental health care delivery. Complex service changes include a shift from institutional to community care, clear positioning of human rights, new models of comprehensive care and approaches including prevention, early intervention, person-centred, recovery-oriented and trauma-informed care, and peer support

Standard dosing regimens of meropenem and piperacillin-tazobactam frequently fail to achieve targeted plasma concentrations in critically ill patients. Extended or continuous regimens are often used to improve target attainment. Although prompt antibiotic initiation is a major determinant of survival, few studies have reported systemic concentrations early after treatment initiation. No prior study

Cerebral perfusion pressure (CPP) management is central to neurocritical care management after traumatic brain injury (TBI). While the Brain Trauma Foundation recommends a target of 60–70 mmHg, it is unclear whether this range reflects the lower limit or the optimal level, when viewed through the prism of cerebrovascular autoregulation. Autoregulation aims at stabilizing cerebral blood flow and can

Endotoxin septic shock is marked by severe organ failure and mortality rate that exceeds fifty percent, underscoring the critical need to tailor management strategies. Monitoring -endotoxin activity can guide the initiation and direction of adjunctive treatment for refractory septic shock through hemoadsorption. Thus, intervening based on the pathophysiological foundation may potentially improve outcomes

Intensive care units (ICUs) contribute significantly to healthcare's environmental footprint, with medications playing a major role. This study performed a comprehensive Material Flow Analysis (MFA) of medications in a large academic ICU to quantify material flows and identify opportunities for sustainability. A single-center MFA was conducted at a 50-bed ICU, analyzing all medications delivered in

Predicting the need for renal replacement therapy (RRT) in acute kidney injury (AKI) remains challenging. The utility of biomarkers was explored during previous studies which were biased as RRT indications relied on clinician opinion rather than evidence. Those studies preceded trials that clarified RRT initiation criteria. We aimed to assess biomarkers in predicting criteria for RRT initiation in

Recent studies have reported paradoxical associations between alcohol use and trauma outcomes, sparking debate in public health, trauma surgery, and emergency medicine [1,2,3]. In a recent paper published in Critical Care, Kazuma Sasaki et al. [4] explored the relationship between pre-injury alcohol consumption and traumatic brain injury (TBI) outcomes of hospitalized patients in Japan, reporting a

AimsTo investigate diabetes family involvement, including supportive and nonsupportive family behaviours in China, and explore the relationships among opposite forms of family involvement, diabetes self‐management and glycaemic control.DesignA cross‐sectional study.MethodsType 2 diabetes patients were recruited from hospitals in Nanjing, Shanghai and Jinan, and communities across China, between April