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Ir-Catalyzed Friedel–Crafts-Type Asymmetric Allylation of Furans Org. Lett. (IF 4.9) Pub Date : 2025-06-03
Yuqi Zhang, Shixiang Sun, Mingyu Zhang, Martin G. Banwell, Xinting Liang, Leijie Zhou -
Beyond 2-Oxazolidinones: Access to N-Unsubstituted Six- and Seven-Membered Analogues Using CO2 and Superbase Catalyst Org. Lett. (IF 4.9) Pub Date : 2025-06-03
Jere K. Mannisto, Johannes Heikkinen, Jukka Puumi, Aleksi Sahari, Pablo Ramírez Veliz, Timo Repo -
Dracomicins, Hybrid Oligosaccharide–Nonribosomal Peptide Antibiotics from Amycolatopsis Species Org. Lett. (IF 4.9) Pub Date : 2025-06-03
Francisco Javier Ortiz-López, Daniel Oves-Costales, José Murillo-Alba, Jesús Martín, Caridad Díaz, Mercedes de la Cruz, Tue Sparholt Jørgensen, Fernando Reyes, Tilmann Weber, Olga GenilloudDracomicins constitute a new class of oligosaccharide–nonribosomal peptide specialized metabolites isolated from the minor actinomycete genus Amycolatopsis. Their structures were determined by NMR, mass spectrometry, and chemical derivatization approaches. Along with their novel chemical scaffolds, dracomicins show unprecedented structural features, including previously unreported β-methyl amino acids
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Elucidation of a Parasitic Proton-Coupled Electron Transfer in a Photocatalytic Benzylic C–H Sulfonamidation Org. Lett. (IF 4.9) Pub Date : 2025-06-03
Nicholas A. Fitzpatrick, Anna M. Howarth, Grzegorz J. Skrzypek, Jisun Lee, Hatice G. Yayla, Patricia Z. Musacchio -
Visible-Light-Induced Generation of p-Quinone Methides via Paternò–Büchi Reaction: Access to Quaternary Centers through Three-Component Coupling Org. Lett. (IF 4.9) Pub Date : 2025-06-03
Mitsumi Takeda, Saki Maejima, Eiji Yamaguchi, Akichika Itoh -
Steric Gating of Excited-State Channel: Controllable AIE/RTP Switching through Tuning π-Bond Twisting Org. Lett. (IF 4.9) Pub Date : 2025-06-03
Hongli Xue, Changqing Ye, Haiyang Huang, Hongli Bao -
1,6-Reduction-Type Hydride Shift/Cyclization Process without Adjacent Heteroatom: Stereoselective Synthesis of Hexahydrofluorene Derivatives via Internal Redox Reaction/Friedel–Crafts Reaction Sequence Org. Lett. (IF 4.9) Pub Date : 2025-06-03
Wakana Matsui, Takayuki Matsuno, Ikuma Takiguchi, Masahiro Anada, Shunsuke Sueki, Kosho Makino, Tomoko Kawasaki-Takasuka, Masahiro Yamanaka, Keiji Mori -
Chiral Phosphoric Acid-Catalyzed Enantioselective Pictet–Spengler Reaction for Concise Synthesis of CF3-Substituted Tetrahydro-β-Carbolines Org. Lett. (IF 4.9) Pub Date : 2025-06-03
Shigenobu Umemiya, Shinnosuke Nara, Masahiro Terada -
Retraction of “Chiral Peropyrene by Selective Dimerization of Phenalenyl” Org. Lett. (IF 4.9) Pub Date : 2025-06-03
Li Sun, Jianwei Liang, Zheng Zhou, Yong YangThe authors retract this letter (DOI: 10.1021/acs.orglett.4c03235) following an institutional investigation into the authorship of this work by the University of Zurich. This investigation concluded that “This work was conceptualized by Prof. Michal Juríček at the University of Zurich and developed by Prof. Yong Yang during his postdoctoral stay in Prof. Juríček’s group, Prof. Joshua C. Walsh made
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Synthesis of Parent Peropyrene and Its Derivatization Org. Lett. (IF 4.9) Pub Date : 2025-06-02
Haruki Sanematsu, Kirill Bulgarevich, Barun Dhara, Kazuo Takimiya -
Triphenylene Diazocines: Butterfly-Type Rigid Photoswitches with Annulated Aromatic Ring Systems and Increased Switching Amplitude Org. Lett. (IF 4.9) Pub Date : 2025-06-02
Artjom Businski, Daniel Hugenbusch, Thuy C. Ta, Ramina Tayaran, Lara Unterriker, Jan-Simon von Glasenapp, Christian Näther, Rainer Herges -
Synthesis of γ-Ketoamides from Nitrones and Ynamides through a Copper-Catalyzed Cascade Reaction Org. Lett. (IF 4.9) Pub Date : 2025-06-02
Abdullah S. Alshreimi, Esther J. Shim, Donald J. Wink, Laura L. Anderson -
Catalytic Asymmetric Intramolecular Domino Allylic O-Alkylation/Allylic Dearomatization of Allyl Aryl Ethers Org. Lett. (IF 4.9) Pub Date : 2025-06-02
Yun-Qiao Zhang, Ying-Long Li, Ke-Xu Wang, Dong-Chao Wang, Hai-Ming Guo -
A Unified Strategy for Transition-Metal-Free Synthesis of Benzothienopyridines, Benzoselenopyridines, and Benzotelluropyridines and Related Analogues Org. Lett. (IF 4.9) Pub Date : 2025-06-02
Zhaoyue Wen, Jianlian Wu, Chun Wang, Bingjie Shen, Mingyue Fu, Xinni Zheng, Cheng Lu, Wei Chen, Tie-Gen Chen -
cis-Diphosphine Ethene Ligand-Ni Complex Catalyzed C-P Cross-Coupling of Aryl Chlorides Org. Lett. (IF 4.9) Pub Date : 2025-06-02
Yumeng Wu, Zhe Tang, Xiaoli Li, Xulu Lv, Jinkui Chai, Fengqian Zhao, Junliang Wu -
Identification of a Privileged Scaffold for Induction of Lysosomal Biogenesis through Synthesis of the Scaffold of Cipadonoid A Org. Lett. (IF 4.9) Pub Date : 2025-06-02
Hong Liang, Xiao Ding, Ying-Tong Di, Zhi-Lin Song, Xin-Yu Tan, Hao-Jing Zang, Li-Li Xu, Zhong-Chao Zhang, Zhen Yang, Xiao-Jiang Hao -
Direct Deoxygenative Formylation of Ketones with Titanium Org. Lett. (IF 4.9) Pub Date : 2025-06-02
Yuquan Wang, Xing-Zhong Shu -
Dynamic Kinetic Asymmetric P–C Coupling of Secondary Phosphine Oxides with Alkenyl Iodides Org. Lett. (IF 4.9) Pub Date : 2025-06-02
Si-Mu Ren, Wen-Jun Yang, Kang Ding, Jie Kang, Jia-Xin Zou, Bo Su -
EDA Complex-Mediated Aerobic Three-Component CDC Reactions of Quinoxalinones under Visible-Light Irradiation Org. Lett. (IF 4.9) Pub Date : 2025-06-02
Xiaoyuan Wan, Richang Wen, Yi Fang, Huawen Huang, Guo-Jun Deng -
Isolation of Noncrystalline Compounds via Adsorption on a Solid Support Org. Lett. (IF 4.9) Pub Date : 2025-06-02
Patrick J. Moon, Joshua R. Belfield, Patrick S. Fier -
Iron-Catalyzed Double Annulation of O-Acyl Oximes with Fumaronitrile for the Synthesis of 4-Cyano-7-azaindoles Org. Lett. (IF 4.9) Pub Date : 2025-06-02
Xian-Heng Ding, Hui Li, Zhen Cui, Cang-Hai Yu, Wen-Ya Xu, En-Jun Qiao, Wan-Bo Jin, Xinyu Lyu, Chun-Bao Miao, Hai-Tao Yang -
Synthesis of Rhodocorane L Using Gold-Catalyzed Dearomative Spirocyclization Org. Lett. (IF 4.9) Pub Date : 2025-06-02
Emily A. Shimizu, Scott D. Rychnovsky -
Copper-Catalyzed Stereoconvergent 1,4-Protosilylation of E/Z Dienes Org. Lett. (IF 4.9) Pub Date : 2025-06-02
Longtao Huang, Yueyuan Wang, Min Gao, Shizhao Xu, Luqing Lin -
Expanding the Diversity of the Terpene Skeleton and Structure through Identification of Noncanonical Class IE and IF Terpene Synthase-Formed Products Org. Lett. (IF 4.9) Pub Date : 2025-06-02
Tohru Abe, Tohru Taniguchi, Daijiro Ueda, Takashi Abe, Tsutomu Sato -
Synthesis, Photophysical, and Redox Properties of Naphtho[2,1-b]-Fused AzaBODIPYs with Ultradeep Lowest Unoccupied Molecular Orbital Levels Org. Lett. (IF 4.9) Pub Date : 2025-05-31
Wanle Sheng, Zhangcui Wang, Guoao Wu, Luying Guo, Xing Guo, Erhong Hao, Lijuan Jiao -
A Two-Enzyme Cascade Directing Polycyclic Assembly in Tetrodecamycin Biosynthesis Org. Lett. (IF 4.9) Pub Date : 2025-05-31
Er Juan Zhao, Salman Khan, Hao Guo, Jia Lin Sun, Ao Zhu, Rui Hua Jiao, Hui Ming Ge, Bo Zhang -
Loading Thiacorrole with Various Aromatic Rings: Enhanced NIR Absorption and Improved OER Activity Org. Lett. (IF 4.9) Pub Date : 2025-05-31
Jiayang Liu, Xinting Liang, Yiqi Zhang, Qizhao Li, Yuxin Li, Tanguy Perrin, Robin D’Herbillié, Xiujun Liu, Xin-Yan Wu, Chengjie Li -
Base-Catalyzed Chemo-, Regio- and Stereoselective Addition of Quinazolinones to Trifluoromethylated Internal Alkynes for Access to N3-Vinylquinazolinones Org. Lett. (IF 4.9) Pub Date : 2025-05-31
Guangyuan Liu, Qiuyu Sheng, Xing Sun, Fangyu Meng, Dan Liu, Linlin Yan, Luo-Sheng Wan, Yirong Zhou -
Dipolar Cycloaddition Approach toward Harmicine-Type Alkaloids: Synthesis and Stereochemical Determination Org. Lett. (IF 4.9) Pub Date : 2025-05-31
Zuming Lin, Luyao Wu, Shengchao Yang, Lili Zhu, Ran Hong, Sha-Hua Huang -
Cobalt-Catalyzed Coupling of Conjugated Dienes and Epoxides with CO Org. Lett. (IF 4.9) Pub Date : 2025-05-31
Ruifang Nie, Xiaotong Shen, Yuan Wen, Suhua Li -
Bioinspired Total Synthesis of Penisuloxazin A Org. Lett. (IF 4.9) Pub Date : 2025-05-30
Zhen Mo, Xiuzhuo Wang, Longchun Liu, Shuai Tian, Yu Tang -
Direct Synthesis of cis-Bicyclic γ-Lactam Derivatives from Iminosugar C-Coumarinyl Glycosides Org. Lett. (IF 4.9) Pub Date : 2025-05-30
Likai Zhou, Lijing Feng, Jilai Wu, Chao Wei, Hua Chen -
Seven Anti-Inflammatory Diarylheptanoid-Indole Alkaloid Hybrids from the Fruits of Amomum maximum Org. Lett. (IF 4.9) Pub Date : 2025-05-30
Shu-Fei Yu, Jin-Na Zhao, Bo Li, Yan-Jun Ding, Lu Chen, Zhi-Hang Wu, Jin-Hui Wang, Li-Bo Wang -
Highly Emissive Luminophores for Direct Chemiluminescence Detection Org. Lett. (IF 4.9) Pub Date : 2025-05-29
Xinxin Huang, Tao Deng, Qiling Wang, Liying Huang, Sixuan Wei, Ying Ma, Chun Cai, Fang Liu -
Lewis Acid-Mediated Deoxygenative Synthesis of Trivalent Sterically Hindered Phosphines from Aldehydes Org. Lett. (IF 4.9) Pub Date : 2025-05-29
Xiaoqiang Wu, Abuduwaili Alimu, Wei Zhong, Tao XU -
Dechlorinative Pyrazinylation of Glycine Derivatives Org. Lett. (IF 4.9) Pub Date : 2025-05-29
Peiqin Zhang, Delin Guan, Youwan Ye, Xiazhen Bao, Xiaolong Zhao, Congde Huo -
Sorbicillalanines A and B, Two [6,5,6] Hybrid-Sorbicillinoid Alkaloids from Deep-Sea-Derived Penicillium sp. Co-Cultured with Sponge-Derived Setosphaeria sp. Org. Lett. (IF 4.9) Pub Date : 2025-05-29
Xiaoyan Pang, Xue Ren, Weihao Chen, Bin Yang, Xuefeng Zhou, Xinpeng Tian, Peng Guo, Junfeng Wang, Yonghong Liu -
Scalable Photoinduced Cycloaddition for the Synthesis of Biorelevant Oxazoles Org. Lett. (IF 4.9) Pub Date : 2025-05-29
Argha Saha, Mattia Bianchi, Emanuele Casali, Debabrata Maiti -
Visible-Light-Mediated Perfluoroalkylation/Thioetherification of [1.1.1]Propellane under Photocatalyst-Free Conditions Org. Lett. (IF 4.9) Pub Date : 2025-05-29
Jiabin Shen, Liang-Feng Yang, Kai Ge, Hao Xu, Chao Shen -
P(O)Me2–Alkenes: From Synthesis to Applications Org. Lett. (IF 4.9) Pub Date : 2025-05-29
Pavlo V. Melnychuk, Oleh V. Kulish, Sofiia I. Pavlish, Vladimir Kubyshkin, Pavel K. Mykhailiuk -
Ni-H-Catalyzed Regioselective Hydroalkylation of Terminal Alkynes with α-Bromo Phosphonates Org. Lett. (IF 4.9) Pub Date : 2025-05-29
Huimin Yang, Niannian Li, Jiayan Jin, Yang Ye -
Synthesis of 2-Phosphorus-Substituted Indoles via Ring Expansion of Benzocyclobutenone Oxime Sulfonates Org. Lett. (IF 4.9) Pub Date : 2025-05-29
Yusuke Kanno, Yumi Yamashita, Akira Sugiyama, Tatsuhiko Kodama, Juri Sakata, Hidetoshi Tokuyama -
Visible-Light-Induced Arylcarboxylation of Activated Alkenes with Aryl Halides and Oxalate Enabled by Electron Donor–Acceptor Complex Formation Org. Lett. (IF 4.9) Pub Date : 2025-05-29
Long Yin, Zhi-Tao Liu, Pei Xu, Tian-Zi Hao, Mei-Hui Cui, Hao Zhang, Xu Zhu -
P450 Biarylitide Synthase ShyB Catalyzes the Cross-Link Between His-C2 and Tyr-O4 on the Precursor Peptide Org. Lett. (IF 4.9) Pub Date : 2025-05-28
Abujunaid Habib Khan, Jabal Rahmat Haedar, Vic Kiselov, Viktors Romanuks, Gints Smits, Stefano Donadio, Chin-Soon Phan -
(Vinyl triflimide)benziodolium Salts: Palladium-Catalyzed Cascade Reactions toward Unsymmetrical Benzils Org. Lett. (IF 4.9) Pub Date : 2025-05-28
Cheng Pan, Xiaoting Liu, Limin Wang, Jianwei Han -
Decatungstate-Catalyzed Photochemical Reactions of Ethenesulfonyl Fluoride: A Linchpin Reagent for C–H Functionalization Org. Lett. (IF 4.9) Pub Date : 2025-05-28
Chima E. Anyaegbu, Joel F. Hooper -
Room-Temperature Copper Cross-Coupling Reactions of Anilines with Aryl Bromides Org. Lett. (IF 4.9) Pub Date : 2025-05-28
Jonas Düker, Nele Petersen, Noah Richter, Paul Feuerer, Teresa Faber, Niklas Hölter, Niklas Kehl, Jan Oboril, Julian Strippel, Alexander Gröer, Nicolas Guimond, Sherif J. Kaldas, Maximilian Lübbesmeyer, Giulio Volpin, Burkhard König, Julius Hillenbrand -
N-Heterocyclic Olefins of Pyrazole and Indazole Org. Lett. (IF 4.9) Pub Date : 2025-05-28
Bolin Zhu, Rouven Woyciechowski, Eike G. Hübner, Felix Lederle, Andreas Schmidt -
Iron-Catalyzed [3 + 2] Annulation of O-Acyl Oximes with 2-Hydroxy-1-Naphthoates for the Synthesis of Benzo[g]indoles Org. Lett. (IF 4.9) Pub Date : 2025-05-28
Zhen Cui, Hui Li, Xian-Heng Ding, Cang-Hai Yu, En-Jun Qiao, Wan-Bo Jin, Wen-Ya Xu, Xinyu Lyu, Chun-Bao Miao, Hai-Tao Yang -
Bistetrazoles Featuring Ultra Thermal Stability Org. Lett. (IF 4.9) Pub Date : 2025-05-28
Jatinder Singh, Richard J. Staples, Jean’ne M. Shreeve -
Iodine-Promoted Oxidative Annulation of Indoles with Trifluoromethyl N-Tosylhydrazone: Access to Trifluoromethylated Pyridazino[3,4-b]indoles Org. Lett. (IF 4.9) Pub Date : 2025-05-28
Yulian Duan, Shi Tang, Dengke Li -
Transition-Metal-Free, Intramolecular Oxidative Coupling of C(sp3)–B with C(sp2)–H Org. Lett. (IF 4.9) Pub Date : 2025-05-28
Tingting Dan, Yuling Liu, Lai Li, Wenwen Yang, Mingyu Yang, Zhangjie Shi -
Diaporlabanoids A–C, Immunosuppressive Dinorlabdane Diterpene Alkaloids with an Unprecedented Carbon Skeleton from Mangrove Endophytic Fungus Diaporthe phaseolorum H3-2 Org. Lett. (IF 4.9) Pub Date : 2025-05-28
Ting Feng, Xiaolin Deng, Zhiyong Xu, Jing Xu -
Photoinduced 1,2-Carbosulfenylation of Alkenes Org. Lett. (IF 4.9) Pub Date : 2025-05-28
Ze-An Peng, Chen Ling, Xuebin Huang, Yu Lu, Xiao-Hui Yang -
A Modular Cyclopentene Annulation Org. Lett. (IF 4.9) Pub Date : 2025-05-28
Adrian E. Samkian, Kasam Poonswat, Scott C. Virgil, Brian M. StoltzWe report a modular three-component annulation among propargyl zinc reagents, unsaturated 1,3-dicarbonyls, and electrophiles to enable rapid construction of highly substituted cyclopentenes. In addition to optimization studies, a range of substrates were investigated. These products can be readily diversified to highlight their synthetic utility.
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NHC-Catalyzed Allylation of Aldehydes with MBH Carbonates and Their Michael Addition–Elimination-Cope Rearrangement Cascade: A Route to rac-Sacubitril Org. Lett. (IF 4.9) Pub Date : 2025-05-28
Tushar B. Kale, Sayali G. Jagtap, Santosh B. Mhaske -
Synthesis and Nucleophilic Ring-Opening of 1,1-Dicyanocyclopropanes: Accessing β-Aminocarbonyl Derivatives from Olefins Org. Lett. (IF 4.9) Pub Date : 2025-05-27
Sebastian Govaerts, Jan Lukas Mayer-Figge, Mohit Chotia, Stefan F. Kirsch, Adrián Gómez-Suárez -
Electrocatalytic 1,6-Difunctionalization of Bicyclopropanes Org. Lett. (IF 4.9) Pub Date : 2025-05-27
Tiantian Wang, Songqing Cao, Fei Xue, Chuan Zhu, Yanni Yue, Chao Feng -
Trichloroacetonitrile-Mediated Oxidation of Sulfides and Benzylic C–H Bonds via Photoexcited Radical Reactions under Clean Conditions Org. Lett. (IF 4.9) Pub Date : 2025-05-27
Jialiang Zhang, Shuaikun Liu, Yingchang Guo, Yi Liu, Kunyi Zhang, Xinqiang Tan, Lizhen Fang -
Balancing Reactivity and Specificity: Fc-Binding O-Acyl Hydroxamate Reagents for Site-Selective Antibody Labeling at Lys248 Org. Lett. (IF 4.9) Pub Date : 2025-05-27
Jin Woo Seo, Sun Hee Park, Jinyoung Kim, TaeJin Lee, Seong-Hyun Park, Ju Hwan Kim, Taedong Han, Sang J. Chung
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