These guidelines aim to assist researchers and research ethics committees/institutional review boards in the ethical conduct of health research with adolescents and young adults (AYA), particularly research with adolescent minors. Inclusion of AYA in research and protection from research harms are essential if, as individuals and as a group, they are to receive the benefits of research. The ethical

Sexual and reproductive health is a fundamental human right for all people, including adolescents and young adults (AYAs). Sexual and reproductive health and rights (SRHR) encompasses the right to comprehensive, medically accurate, and evidence-based sexual health information and healthcare services, as well as the ability to understand and exercise these rights. SRHR are essential to AYA’s emotional

Despite increasing rates of Neisseria gonorrheae and Chlamydia trachomatis nationally, prior studies indicate suboptimal screening in pediatric and young adult settings. This study surveyed provider attitudes, knowledge, practices, and barriers around sexually transmitted infection testing to identify potential contributing factors.

Physical activity (PA) is recommended for the management of women with polycystic ovary syndrome (PCOS). However, it is not known whether PA modulates the risk of components of PCOS diagnostic criteria during adolescence.

This study is the first to examine the impact of structural racism from historic redlining practices on present-day perceived stress in adolescents.

Noncommunicable diseases (NCDs) such as cardiovascular diseases, diabetes, and cancers are major global health concerns, disproportionately impacting low- and middle-income countries (LMICs). Adolescents in LMICs are particularly vulnerable due to urbanization, lifestyle changes, and limited preventive care access. This study evaluates the effectiveness of educational interventions in improving adolescents'

Violence prevention requires robust data on trends in different forms of violence and measures of progress toward reduction across subgroups of the population. This study aimed to investigate trends and related socioeconomic inequalities in parental physical aggression and involvement in physical fights among adolescents.

To explore the importance of and interconnected nature between the reasons and motivations underlying suicide behaviors among adolescents in Hong Kong.

To evaluate temporal trends and drivers of mortality among younger adults (aged 18–39), from 1999 to 2021.

The U.S. immigrants are at high risk for human papillomavirus (HPV) infection and death from HPV-related diseases. Children of immigrants have lower HPV vaccine initiation and completion rates compared to children of U.S.-born parents. Previous research suggests that sociocultural factors may play a role in these disparities, but this is still largely understudied. This study examines the relationship

Since Crisis Pregnancy Centers (CPCs) are known to target college and university (CU) students, the purpose of this analysis was to describe the spatial proximity between CUs and CPCs in the United States by driving distance.

E-cigarette use among adolescents and young adults (AYAs) remains prevalent in the United States and is linked with combustible tobacco product use. This study examines sociodemographic differences (i.e., sex, age, sexual identity, transgender identity, race, ethnicity, and income) in transitions from e-cigarette use to other forms of tobacco use among AYAs from 2014 to 2023.

Social media present opportunities to intervene on harmful rape myth beliefs among adolescents and young adults, such as through digital bystander intervention.

The United States Advisory Committee on Immunization Practices recommends routine vaccination against meningococcal serogroups A, C, W, and Y for all aged 11–12 years (with a booster dose for age 16 years) and vaccination against meningococcal serogroup B (MenB) for ages 16–23 years under shared clinical decision-making (SCDM). Considering the Advisory Committee on Immunization Practices' ongoing revision

Using nationally representative surveys with internet-using children aged 12–17 across 13 countries in Eastern and Southern Africa and Southeast Asia, the study aimed to examine attitudinal factors associated with sexting-related risk perception and analyze the extent to which risk perception is correlated with sexting behavior.

Family acceptance is a crucial protective factor for transgender and gender diverse (TGD) youth well-being. Few studies examine how families react to gender transitions by youth. This study aimed to examine whether families react differently when youth report different gender identities or when youth report gender-nonconforming expressions.

Weight stigma is a common experience for adolescents at high weight statuses. Prior research regarding experiences of weight stigma in adolescence has been in primarily homogenous samples. The present study sought to characterize weight stigma experiences and internalization in adolescents from low-income backgrounds. This was done by reporting on teen's experiences of weight stigma in daily life and

This study investigated mental health outcomes among young adults who experienced direct police contact — including unfair or aggressive policing — in the past year.

Sexual minority women and gender diverse youth in the United States experience disparities in sexual and reproductive health. We evaluated whether sexual partner type, identity, and attraction were associated with healthcare disclosure, and whether healthcare disclosure was associated with sexual and reproductive healthcare receipt in a sample of sexual minority and gender diverse youth aged 18–24

Research has rarely examined biobehavioral factors in mitigating substance use (SU) risks associated with discrimination among racially and ethnically minoritized youth. This study investigated sleep duration as a potential moderator of the association between multiple forms of discrimination based on race and ethnicity, sexual orientation, and weight (i.e., multiple discrimination) and subsequent

The purpose of this systematic review is to assess evidence for an association between opioid misuse and suicide-related outcomes among youth and young adults (aged 12–30 years). A Boolean search strategy of eligible publications from January 1990 to June 2024 identified 2,696 independent citations. An additional 10 were identified through reference screening. A total of 55 publications met the inclusion

Existing literature has provided limited and inconsistent findings regarding disparities in mental health and mental health care utilization among racial and ethnic subgroups of sexual and gender minority adolescents (SGMA). This study aimed to investigate racial and ethnic disparities in mental health and care utilization among SGMA.

Rates of internalizing symptoms and suicide risk are increasing among emerging adult populations. The current study highlighted resiliency factors, including prosocial behavior and self-esteem, and their longitudinal associations with depressive symptoms, anxiety symptoms, and suicidal risk.

Sexual and gender minority adolescents (SGMA) are at heighted risk for suicide ideation (SI) and nonsuicidal self-injury ideation (NSSII) compared to their heterosexual and cisgender counterparts. Oppression-based stressors are posited to explain these disparities. However, there is limited research examining protective factors that mitigate the impact of oppression-based stressors. We conducted a

Lesbian, gay, bisexual, transgender, and queer/questioning (LGBTQ) youth are at high suicide risk. Family/peer connectedness may be protective factors; few studies assess social connectedness within cisgender lesbian, gay, bisexual, and queer (cis-LGBQ) and transgender and gender-diverse (TGD) samples. This study aims to identify associations between family/peer connectedness and suicidal thoughts/behaviors

We hypothesized that extended exposure to the COVID-19 pandemic and government lockdown was associated with increased depression and anxiety symptoms among South African adolescents and a sense of school belonging mediated these relationships. We also hypothesized that poor mental health or school belonging impacted alcohol consumption.

Caloric restriction and excessive exercise create an energy imbalance with medical sequelae in restrictive eating disorders. We examined the effect of acute and chronic energy imbalance on admission illness severity and refeeding outcomes in adolescents and young adults with anorexia nervosa (AN) and atypical AN.

Evidence on the effect of menstrual health and hygiene (MHH) interventions on education is scarce. This trial assessed the effect of a multicomponent intervention on school attendance, urogenital health, and other wellbeing outcomes among schoolgirls in rural Gambia.

Opioid use disorder (OUD) is a growing public health crisis. However, no study to date has systematically evaluated the burden of OUD among adolescents and young adults (AYAs). We aimed to report the global level and trends of OUD burden among AYAs.

Investigating drinking motives among minors across various countries is crucial for understanding the broader social context of alcohol consumption. Thus, this study aimed to examine the differences and similarities in drinking motives among 15–16-year-old adolescents who consume alcohol across 16 European countries.

Childhood adversity is linked to poorer adult health; prior research has established a reciprocal association between health and civic engagement. However, little research has examined the relationship between adverse childhood experiences (ACEs) and civic engagement. We examined whether ACEs are associated with civic engagement at ages 18–26 years and evaluated the potential moderating role of perceived

Many prior studies on adolescent electronic nicotine delivery systems (ENDS) did not differentiate regular users from light users or experimenters. This study was conducted to investigate the longitudinal behavioral transitions among adolescent ENDS users.

Youth placed in U.S. juvenile detention facilities face multilevel barriers that contribute to disparate sexual and reproductive health (SRH) outcomes when compared to their peers in the general adolescent population. Minimal information is available about evidence-based interventions that have been effective in changing these outcomes. The aim of this scoping review was to focus on the current state