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Transcription-templated assembly of the nucleolus in the Caenorhabditis elegans embryo Proc. Natl. Acad. Sci. U.S.A. (IF 9.4) Pub Date : 2025-05-30
Nishant KodanRabeya HussainiStephanie C. WeberJane KondevLishibanya MohapatraaSchool of Physics and Astronomy, College of Science, Rochester Institute of Technology, Rochester, NY 14623bDepartment of Physics, New York University, New York, NY 10003cDepartment of Biology, McGill University, Montreal, QC H3A 1B1, CanadadDepartment of Physics, McGill University, Montreal, QC H3A 2T8, CanadaeDepartmentProceedings of the National Academy of Sciences, Volume 122, Issue 22, June 2025. SignificanceHow membraneless organelles like nucleolus assemble within cells is not well understood. Recent experiments suggest that transcription of ribosomal RNA actively drives nucleolar assembly. Our proposed model of active transcription-templated ...
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Can increasing the size and flexibility of a molecule reduce decoherence and prolong charge migration? Proc. Natl. Acad. Sci. U.S.A. (IF 9.4) Pub Date : 2025-05-30
Alan ScheideggerNikolay V. GolubevJiří J. L. VaníčekaLaboratory of Theoretical Physical Chemistry, Institut des Sciences et Ingénierie Chimiques, Ecole Polytechnique Fédérale de Lausanne, Lausanne CH-1015, SwitzerlandbDepartment of Physics, University of Arizona, Tucson, AZ 85721Proceedings of the National Academy of Sciences, Volume 122, Issue 22, June 2025. SignificanceTogether with tunneling and entanglement, coherence belongs among the hallmarks of quantum mechanics and among the prerequisites for building quantum devices. In attochemistry, the loss of electronic coherence induced by nuclear motion ...
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Solution structure and synaptic analyses reveal determinants of bispecific T cell engager potency Proc. Natl. Acad. Sci. U.S.A. (IF 9.4) Pub Date : 2025-05-30
Alexander LeithnerOskar StauferTanmay MitraFalk LibertaSalvatore ValvoMikhail KutuzovHannah DadaJacob SpaethWeijie ZhouFelix SchieleSophia ReindlHerbert NarStefan HoererMaureen CramesStephen ComeauDavid YoungSarah LowEdward JenkinsSimon J. DavisDavid KlenermanAndrew NixonNoah PefaurDavid WyattOmer DushekSrinath KasturiranganMichael L. DustinaThe Kennedy Institute of Rheumatology, Nuffield DepartmentProceedings of the National Academy of Sciences, Volume 122, Issue 22, June 2025. SignificanceBispecific T cell engagers (TcEs) are immunotherapeutic drugs that trigger the destruction of cancer cells by linking T cells to cancer cells through specific surface molecules (antigens). We designed a series of TcEs with varying distances ...
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Estimating wage disparities using foundation models Proc. Natl. Acad. Sci. U.S.A. (IF 9.4) Pub Date : 2025-05-30
Keyon VafaSusan AtheyDavid M. BleiaHarvard Data Science Initiative, Harvard University, Cambridge, MA 02138bGraduate School of Business, Stanford University, Stanford, CA 94305cStanford Institute for Human-Centered Artificial Intelligence, Stanford University, Stanford, CA 94305dDepartment of Computer Science, Columbia University, New York, NY 10027eDepartment of Statistics, Columbia University, NewProceedings of the National Academy of Sciences, Volume 122, Issue 22, June 2025. SignificanceUnderstanding differences in outcomes between social groups—such as wage gaps between men and women—remains a central challenge in social science. While researchers have long studied how observable factors contribute to these differences, ...
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Exploring diverse supramolecular tessellation through hierarchical assemblies of nonalternant nanographene Proc. Natl. Acad. Sci. U.S.A. (IF 9.4) Pub Date : 2025-05-30
Jian SunZiqi DengDavid Lee PhillipsJunzhi LiuaDepartment of Chemistry, The University of Hong Kong - Chinese Academy of Sciences Joint Laboratory on New Materials and Shanghai-Hong Kong Joint Laboratory on Chemical Synthesis, The University of Hong Kong, Hong Kong 999077, ChinabState Key Laboratory of Synthetic Chemistry, The University of Hong Kong, Hong Kong 999077, ChinacMaterials Innovation InstituteProceedings of the National Academy of Sciences, Volume 122, Issue 22, June 2025. SignificanceThe tessellated material is poised to become a fascinating subject in materials science, following the initial exploration of quasicrystals. Specifically, supramolecular tessellation at the molecular level has primarily been observed in ...
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Environmental DNA adsorption to chitin can promote horizontal gene transfer by natural transformation Proc. Natl. Acad. Sci. U.S.A. (IF 9.4) Pub Date : 2025-05-30
Jacob D. HoltYixuan PengTriana N. DaliaAnkur B. DaliaCarey D. NadellaDepartment of Biological Sciences, Dartmouth, Hanover, NH 03755bDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, NH 03755cDepartment of Biology, Indiana University, Bloomington, IN 47405Proceedings of the National Academy of Sciences, Volume 122, Issue 22, June 2025. SignificanceThe human pathogen and marine microbeVibrio choleraehas been shown to activate extracellular DNA uptake and transformation when in contact with chitin, the most abundant structural biomaterial in the oceans and a primary source of nutrition ...
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Genomic analyses identify 15 risk loci and reveal HDAC2, SOX2-OT, and IGF2BP2 in a naturally occurring canine model of gastric cancer Proc. Natl. Acad. Sci. U.S.A. (IF 9.4) Pub Date : 2025-05-30
Shawna R. CookSanne HugenJessica J. HaywardThomas R. FamulaJanelle M. BelangerElizabeth McNielHille FietenAnita M. OberbauerPeter A. J. LeegwaterElaine A. OstranderPaul J. J. MandigersJacquelyn M. EvansaBaker Institute for Animal Health, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853bDepartment of Biomedical Sciences, College of Veterinary Medicine, Cornell University, IthacaProceedings of the National Academy of Sciences, Volume 122, Issue 22, June 2025. SignificanceGastric cancer is the fifth most common cause of human cancer deaths, but the genetic underpinnings are poorly understood. Harnessing the genetic homogeneity of purebred dogs, we identify 18 loci governing gastric cancer susceptibility in a ...
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Himalayan “S-type” granite generated from I-type sources Proc. Natl. Acad. Sci. U.S.A. (IF 9.4) Pub Date : 2025-05-30
Huixia DingZeming ZhangMatthew J. KohnaState Key Laboratory of Geological Processes and Mineral Resources, and School of Earth Sciences and Resources, China University of Geosciences, Beijing 100083, ChinabInstitute of Geology, Chinese Academy of Geological Sciences, Beijing 100037, ChinacDepartment of Geosciences, Boise State University, Boise, ID 83725Proceedings of the National Academy of Sciences, Volume 122, Issue 22, June 2025. SignificanceClassically, granites are separated into two broad categories—“I-type” vs. “S-type”—representing different igneous vs. (meta)sedimentary rock sources for melting. Their geochemistry differs for diverse geochemical systems. Himalayan granites ...
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Proofreading and single-molecule sensitivity in T cell receptor signaling by condensate nucleation Proc. Natl. Acad. Sci. U.S.A. (IF 9.4) Pub Date : 2025-05-30
William L. WhiteHailemikael K. YirdawAriel J. Ben-SassonJay T. GrovesDavid BakerHao Yuan KuehaDepartment of Bioengineering, University of Washington, Seattle, WA 98195bInstitute for Protein Design, University of Washington, Seattle, WA 98195cDepartment of Chemistry, University of California Berkeley, Berkeley, CA 94720dInstitute for Digital Molecular Analytics and Science, Nanyang Technological UniversityProceedings of the National Academy of Sciences, Volume 122, Issue 22, June 2025. SignificanceTo fight infections and cancer, T cells must selectively recognize low levels of foreign peptides from pathogens or cancer cells, but the mechanisms that enable these properties remain unclear. Using computational modeling and experiments, we ...
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Rhomboid-mediated cleavage of the immune receptor XA21 protects grain set and male fertility in rice Proc. Natl. Acad. Sci. U.S.A. (IF 9.4) Pub Date : 2025-05-30
Satyam VergishXiaoen HuangGuiyun ZhangBeatriz de Toledo FranceschiJian-Liang LiXiao-Xia WuJoana NurajJose C. Huguet-TapiaApekshya ParajuliXiuhua ChenRitu ShekharDali LiuWu-Ming XiaoShijuan DouGuo-zhen LiuErica M. GossLiya PiSixue ChenKaren E. KochWen-Yuan SongaDepartment of Plant Pathology, Institute of Food and Agricultural Sciences, University of Florida, Gainesville, FL 32611bIntegrative BioinformaticsProceedings of the National Academy of Sciences, Volume 122, Issue 22, June 2025. SignificanceThe protection of key developmental processes from the immune system, while allowing the immune system to defend against pathogens, is central for the survival and reproduction of nearly all multicellular organisms. The rice immune receptor ...
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Task difficulty modulates the effect of mind wandering on phase dynamics Proc. Natl. Acad. Sci. U.S.A. (IF 9.4) Pub Date : 2025-05-30
Zhengkun LongGeorg NorthoffXiaolan FuaState Key Laboratory of Cognitive Science and Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing 100101, ChinabDepartment of Psychology, University of Chinese Academy of Sciences, Beijing 100049, ChinacSchool of Psychology, Shenzhen University, Shenzhen, Guangdong 518060, ChinadMind, Brain Imaging and Neuroethics Research Unit, The Royal’sProceedings of the National Academy of Sciences, Volume 122, Issue 22, June 2025. SignificanceWe demonstrate that external (sensory and motor processing) and internal cognition (mind wandering) are dynamically interdependent. Easier external tasks require fewer executive resources, leaving more cognitive resources for internal mind ...
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Modular arrangement of synaptic and intrinsic homeostatic plasticity within visual cortical circuits Proc. Natl. Acad. Sci. U.S.A. (IF 9.4) Pub Date : 2025-05-30
Wei WenAdriana M. PradaGina G. TurrigianoaDepartment of Biology, Brandeis University, Waltham, MA 02453Proceedings of the National Academy of Sciences, Volume 122, Issue 22, June 2025. SignificanceHomeostatic plasticity maintains normal brain functions by constraining various network features of neural circuits, yet how this is realized on the cellular level remains unknown. Synaptic and intrinsic forms of homeostatic plasticity adjust ...
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CRISPR screen reveals a simultaneous targeted mechanism to reduce cancer cell selenium and increase lipid oxidation to induce ferroptosis Proc. Natl. Acad. Sci. U.S.A. (IF 9.4) Pub Date : 2025-05-30
Sophia M. LamperisKaylin M. McMahonAndrea E. CalvertJonathan S. RinkKarthik VasanMadhura R. PandkarEliana U. CrentsilZachary R. ChalmersNatalie R. McDonaldCameron J. KosmalaMarcelo G. BoniniDaniela MateiLeo I. GordonNavdeep S. ChandelC. Shad ThaxtonaDepartment of Urology, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611bSimpson Querrey Institute for BioNanotechnology, NorthwesternProceedings of the National Academy of Sciences, Volume 122, Issue 22, June 2025. SignificanceFerroptosis is an iron-dependent cell death mechanism that results from increased oxidation of cell membrane lipids. We conducted a CRISPR-based positive selection screen in clear cell ovarian cancer cells treated with a nanoparticle drug to ...
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Phage-induced protection against lethal bacterial reinfection Proc. Natl. Acad. Sci. U.S.A. (IF 9.4) Pub Date : 2025-05-30
Yikun XingHaroldo J. Hernandez SantosLing QiuSamantha R. RitterJacob J. ZulkRachel LahowetzKathryn A. PatrasAusten L. TerwilligerAnthony W. MaressoaTAILOR Labs, Baylor College of Medicine, Houston, TX 77030bDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX 77030cAlkek Center for Metagenomics and Microbiome Research, Baylor College of Medicine, Houston, TX 77030Proceedings of the National Academy of Sciences, Volume 122, Issue 22, June 2025. SignificanceIn 2021, antimicrobial-resistant bacteria were responsible for 1.14 million deaths and associated with 4.71 million deaths globally. Patients who experience sepsis often face a higher risk of reinfections and hospital readmissions. To combat ...
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Oxr1 and Ncoa7 regulate V-ATPase to achieve optimal pH for glycosylation within the Golgi apparatus and trans-Golgi network Proc. Natl. Acad. Sci. U.S.A. (IF 9.4) Pub Date : 2025-05-30
Shin-ichiro YoshimuraTomoaki SobajimaMasataka KuniiAkihiro HaradaaDepartment of Cell Biology, Graduate School of Medicine, The University of Osaka, Suita 565-0871, Osaka, JapanProceedings of the National Academy of Sciences, Volume 122, Issue 22, June 2025. SignificanceIn the secretory pathway, the pH within organelles is gradually acidified, starting at 7.1 to 7.2 in the endoplasmic reticulum, decreasing to 6.0 to 6.7 in the Golgi apparatus/trans-Golgi network (Golgi/TGN), and reaching 4.5 to 5.0 in ...
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Label-free high-throughput live-cell sorting of genome-wide random mutagenesis libraries for metabolic traits by Raman flow cytometry Proc. Natl. Acad. Sci. U.S.A. (IF 9.4) Pub Date : 2025-05-30
Xixian WangSen WangZhidian DiaoXibao HouYanhai GongQing SunJiaping ZhangLihui RenYuandong LiYuetong JiWei ShenYifeng YinShi HuangXiaojin SongQiu CuiYingang FengJian XuBo MaaState Key Laboratory of Photoelectric Conversion and Utilization of Solar Energy, Key Laboratory of Shandong Energy Biological Genetic Resources, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of SciencesProceedings of the National Academy of Sciences, Volume 122, Issue 22, June 2025. SignificanceSorting cells with target metabolic functions from a mutant pool exhibiting substantial genetic diversity is often the rate-limiting step in synthetic biology. Here, we developed a label-free, high-throughput Raman-activated cell sorting ...
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In This Issue Proc. Natl. Acad. Sci. U.S.A. (IF 9.4) Pub Date : 2025-06-03
Proceedings of the National Academy of Sciences, Volume 122, Issue 22, June 2025.
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An AI-assisted fluorescence microscopic system for screening mitophagy inducers by simultaneous analysis of mitophagic intermediates Nat. Commun. (IF 14.7) Pub Date : 2025-06-04
Yicheng Wang, Pengfei Song, Heqing Zhou, Pengwei Wang, Yan Li, Zhiyong Shao, Lu Wang, Yan You, Zuhai Lei, Jinhua Yu, Cong Li -
Control of tissue flows and embryo geometry in avian gastrulation Nat. Commun. (IF 14.7) Pub Date : 2025-06-04
Guillermo Serrano Nájera, Alex M. Plum, Ben Steventon, Cornelis J. Weijer, Mattia Serra -
Cytoreductive surgery and hyperthermic intrathoracic chemotherapy in thymic epithelial tumors with pleural spread or recurrence: a prospective, single-arm, phase II study Nat. Commun. (IF 14.7) Pub Date : 2025-06-04
Shuai Wang, Xinyu Yang, Jiahao Jiang, Fei Liang, Yuansheng Zheng, Yongqiang Ao, Jian Gao, Hao Wang, Lijie Tan, Jianyong Ding -
FXYD2 marks and regulates maturity of β cells via ion channel-mediated signal transduction Nat. Commun. (IF 14.7) Pub Date : 2025-06-04
Clarissa Tacto, Meghan Tahbaz, Andrew Salib, Shudi Wang, Fritz Cayabyab, Jinhyuk Choi, Kiyoka Kim, Yu Hamba, Harvey Perez, Paul D. Gershon, Robert Damoiseaux, Tae Gyu Oh, Eiji Yoshihara -
OsPRMT6b balances plant growth and high temperature stress by feedback inhibition of abscisic acid signaling Nat. Commun. (IF 14.7) Pub Date : 2025-06-04
Xin Jin, Qibing Lin, Xinyue Zhang, Shuang Zhang, Weiwei Ma, Peike Sheng, Limin Zhang, Minxi Wu, Xudong Zhu, Zhiwei Li, Bojuan Liu, Jiachang Wang, Yupeng Wang, Kun Dong, Ming Yu, Yulong Ren, Zhijun Cheng, Cailin Lei, Xiuping Guo, Xin Wang, Haiyang Wang, Fu-Qing Wu, Shanshan Zhu, Jianmin Wan -
Identifying T cell antigen at the atomic level with graph convolutional network Nat. Commun. (IF 14.7) Pub Date : 2025-06-04
Jinhao Que, Guangfu Xue, Tao Wang, Xiyun Jin, Zuxiang Wang, Yideng Cai, Wenyi Yang, Meng Luo, Qian Ding, Jinwei Zhang, Yilin Wang, Yuexin Yang, Fenglan Pang, Yi Hui, Zheng Wei, Jun Xiong, Shouping Xu, Yi Lin, Haoxiu Sun, Pingping Wang, Zhaochun Xu, Qinghua Jiang -
Molecular basis of the urate transporter URAT1 inhibition by gout drugs Nat. Commun. (IF 14.7) Pub Date : 2025-06-04
Yang Suo, Justin G. Fedor, Han Zhang, Kalina Tsolova, Xiaoyu Shi, Kedar Sharma, Shweta Kumari, Mario Borgnia, Peng Zhan, Wonpil Im, Seok-Yong Lee -
A versatile information retrieval framework for evaluating profile strength and similarity Nat. Commun. (IF 14.7) Pub Date : 2025-06-04
Alexandr A. Kalinin, John Arevalo, Erik Serrano, Loan Vulliard, Hillary Tsang, Michael Bornholdt, Alán F. Muñoz, Suganya Sivagurunathan, Bartek Rajwa, Anne E. Carpenter, Gregory P. Way, Shantanu Singh -
Realizing mechanical frustration at the nanoscale using DNA origami Nat. Commun. (IF 14.7) Pub Date : 2025-06-04
Anirudh S. Madhvacharyula, Ruixin Li, Alexander A. Swett, Yancheng Du, Seongmin Seo, Friedrich C. Simmel, Jong Hyun Choi -
Androgens inhibit protective CD8+ T cell responses against pre-erythrocytic malaria parasites in mice Nat. Commun. (IF 14.7) Pub Date : 2025-06-04
Caroline J. Duncombe, Nilasha Sen, Felicia N. Watson, Alen S. Poehlman, Erik D. Layton, Kenneth Boey, Ethan N. Conrad, Anya C. Kalata, A. Mariko Seilie, Kimberly A. Dill-McFarland, Chetan Seshadri, Melanie J. Shears, Sean C. Murphy -
Efficacy of clindamycin and LACTIN-V for in vitro fertilization patients with vaginal dysbiosis: a randomised double-blind, placebo-controlled multicentre trial Nat. Commun. (IF 14.7) Pub Date : 2025-06-04
Thor Haahr, Nina la Cour Freiesleben, Mette Brix Jensen, Helle Olesen Elbaek, Birgit Alsbjerg, Rita Laursen, Lisbeth Prætorius, Henriette Svarre Nielsen, Anja Pinborg, Vibeke Hartvig Boujida, Thomas Roland Pedersen, Axel Skafte-Holm, Jørgen Skov Jensen, Peter Humaidan -
Ciprofloxacin resistance rapidly declines in nfxB defective clinical strains of Pseudomonas aeruginosa Nat. Commun. (IF 14.7) Pub Date : 2025-06-04
Sara Hernando-Amado, Pablo Laborda, Ruggero La Rosa, Søren Molin, Helle Krogh Johansen, José Luis Martínez -
Distinct spatially organized striatum-wide acetylcholine dynamics for the learning and extinction of Pavlovian associations Nat. Commun. (IF 14.7) Pub Date : 2025-06-04
Safa Bouabid, Liangzhu Zhang, Mai-Anh T. Vu, Kylie Tang, Benjamin M. Graham, Christian A. Noggle, Mark W. Howe -
IvoryOS: an interoperable web interface for orchestrating Python-based self-driving laboratories Nat. Commun. (IF 14.7) Pub Date : 2025-06-04
Wenyu Zhang, Lucy Hao, Veronica Lai, Ryan Corkery, Jacob Jessiman, Jiayu Zhang, Junliang Liu, Yusuke Sato, Maria Politi, Matthew E. Reish, Rebekah Greenwood, Noah Depner, Jiyoon Min, Rama El-khawaldeh, Paloma Prieto, Ekaterina Trushina, Jason E. Hein -
Efficient generation of germline chimeras in a non-rodent species using rabbit induced pluripotent stem cells Nat. Commun. (IF 14.7) Pub Date : 2025-06-04
Hong-Thu Pham, Florence Perold, Yannicke Pijoff, Nathalie Doerflinger, Sylvie Rival-Gervier, Maëlle Givelet, Anaïs Moulin, Manon Ressaire, Emilie Da Silva Fernandes, Valeska Bidault, Luc Jouneau, Véronique Duranthon, Florence Wianny, Bertrand Pain, Ingrid Plotton, Thierry Joly, Marielle Afanassieff, Pierre Savatier, Nathalie Beaujean -
Single cell profiling of human airway identifies tuft-ionocyte progenitor cells displaying cytokine-dependent differentiation bias in vitro Nat. Commun. (IF 14.7) Pub Date : 2025-06-04
Viral S. Shah, Avinash Waghray, Brian Lin, Atharva Bhagwat, Isha Monga, Michal Slyper, Bruno Giotti, Sunghyun Kim, Dawei Sun, Ke Xu, Eric Park, Mohamad Bairakdar, Jiajie Xu, Julia Waldman, Danielle Dionne, Lan T. Nguyen, Wendy Lou, Peiwen Cai, Christoph Muus, Jiawei Sun, Manalee V. Surve, Lujia Cha Cha Yang, Orit Rozenblatt-Rosen, Toni M. Delorey, Srinivas Vinod Saladi, Aviv Regev, Jayaraj Rajagopal -
The mechanism of acetyl-CoA synthase through the lens of a nickel model system Nat. Commun. (IF 14.7) Pub Date : 2025-06-04
Shounak Nath, Leonel Griego, Liviu M. Mirica -
Evolution and transmission dynamics of wild poliovirus in Pakistan and Afghanistan (2012-2023) Nat. Commun. (IF 14.7) Pub Date : 2025-06-04
David Jorgensen, Margarita Pons-Salort, Muhammad Salman, Adnan Khurshid, Yasir Arshad, Nayab Mahmood, Darlan da Silva Candido, Steve Kroiss, Hil Lyons, Nicholas C. Grassly, Muhammad Masroor Alam -
Inferring internal states across mice and monkeys using facial features Nat. Commun. (IF 14.7) Pub Date : 2025-06-04
Alejandro Tlaie, Muad Y. Abd El Hay, Berkutay Mert, Robert Taylor, Pierre-Antoine Ferracci, Katharine Shapcott, Mina Glukhova, Jonathan W. Pillow, Martha N. Havenith, Marieke L. Schölvinck -
Epithelial GREMLIN1 disrupts intestinal epithelial-mesenchymal crosstalk to induce a wnt-dependent ectopic stem cell niche through stromal remodelling Nat. Commun. (IF 14.7) Pub Date : 2025-06-04
Eoghan J. Mulholland, Hayley L. Belnoue-Davis, Gabriel N. Valbuena, Nuray Gunduz, Amelia Ligeza, Muyang Lin, Sujata Biswas, Ester Gil Vasquez, Sulochana Omwenga, Nadia Nasreddin, Michael C. Hodder, Lai Mun Wang, Aik Seng Ng, Elizabeth Jennings, Kim S. Midwood, Neesha Dedi, Shazia Irshad, Rachel A. Ridgway, Toby J. Phesse, James East, Ian PM Tomlinson, Gareth CG Davies, Owen J. Sansom, Simon J. Leedham -
Assembly and breakage of head-to-head double hexamer reveals mpox virus E5-catalyzed DNA unwinding initiation Nat. Commun. (IF 14.7) Pub Date : 2025-06-04
Yingxian Cheng, Pu Han, Qi Peng, Ruili Liu, Hao Liu, Bin Yuan, Yunfei Zhao, Lu Kuai, Jianxun Qi, Kai Miao, Yi Shi, George Fu Gao, Han Wang -
Exponentially-enhanced quantum sensing with many-body phase transitions Nat. Commun. (IF 14.7) Pub Date : 2025-06-03
Saubhik Sarkar, Abolfazl Bayat, Sougato Bose, Roopayan Ghosh -
Three dimensional multiscalar neurovascular nephron connectivity map of the human kidney across the lifespan Nat. Commun. (IF 14.7) Pub Date : 2025-06-03
Liam McLaughlin, Bo Zhang, Siddharth Sharma, Amanda L. Knoten, Madhurima Kaushal, Jeffrey M. Purkerson, Heidie L. Huyck, Gloria S. Pryhuber, Joseph P. Gaut, Sanjay Jain -
Brillouin-induced Kerr frequency comb in normal dispersion fiber Fabry Perot resonators Nat. Commun. (IF 14.7) Pub Date : 2025-06-03
Thomas Bunel, Julien Lumeau, Antonin Moreau, Arnaud Fernandez, Olivier Llopis, Germain Bourcier, Auro M. Perego, Matteo Conforti, Arnaud Mussot -
Reaction-induced dynamic evolution of PtIn/SiO2 catalyst for propane dehydrogenation Nat. Commun. (IF 14.7) Pub Date : 2025-06-03
Tao Zhou, Han Yan, Wenjie Li, Wenjian Zhang, Hongtao He, Sunpei Hu, Ruyang Wang, Tianci Xiao, Limin Liu, Lijun Zhang, Wenlong Wu, Chengyuan Liu, Xusheng Zheng, Yang Pan, Jie Zeng, Xu Li -
Dynamic mechanical modulation of chiroptical structures via linearly assembled plasmonic nanoparticles on birefringent polymer films Nat. Commun. (IF 14.7) Pub Date : 2025-06-03
Xiao Meng, Yisheng He, Botyo Dimitrov, Bowen Jin, Zhenghua Zhu, Liang Yuan, Vladimir V. Tsukruk, Chunhong Ye -
Concealable physical unclonable functions using vertical NAND flash memory Nat. Commun. (IF 14.7) Pub Date : 2025-06-03
Sung-Ho Park, Ryun-Han Koo, Yeongheon Yang, Jiseong Im, Jonghyun Ko, Jong-Ho Lee -
Antigen persistence and TLR stimulation contribute to induction of a durable HIV-1-specific neutralizing antibody response Nat. Commun. (IF 14.7) Pub Date : 2025-06-03
Kenta Matsuda, Mitra Harrison, Eleanor Wettstein, Jessica Pederson, Alyssa A. Pullano, Lyuba Bolkhovitinov, Breanna Kim, Isabel Steinberg, Trevor Griesman, Sarah Stuccio, Daniel Rogan, Andy Patamawenu, Tulley Shofner, Nathaniel E. Wright, Jonathan D. Webber, Freya van’t Veer, Rachel Roenicke, Emma Koory, Peyton M. Roeder, Ellison Ober, Benjamin Leach, Yaroslav Tsybovsky, Tyler Stephens, Ivan Del Moral-Sanchez -
The geometric-electronic coupled design of diatomic catalyst towards oxygen reduction reaction Nat. Commun. (IF 14.7) Pub Date : 2025-06-03
Yan Liu, Yan Yang, Xuanni Lin, Yutao Lin, Zhiwen Zhuo, Dong Liu, Junjie Mao, Jun Jiang -
Polyketide synthase-derived sphingolipids mediate microbiota protection against a bacterial pathogen in C. elegans Nat. Commun. (IF 14.7) Pub Date : 2025-06-03
Lena Peters, Moritz Drechsler, Michael A. Herrera, Jing Liu, Barbara Pees, Johanna Jarstorff, Anna Czerwinski, Francesca Lubbock, Georgia Angelidou, Liesa Salzer, Karlis Arturs Moors, Nicole Paczia, Yi-Ming Shi, Hinrich Schulenburg, Christoph Kaleta, Michael Witting, Manuel Liebeke, Dominic J. Campopiano, Helge B. Bode, Katja Dierking -
Serotonergic neurons regulate the Drosophila vascular niche to control immune stress hematopoiesis Nat. Commun. (IF 14.7) Pub Date : 2025-06-03
Xiaohui Liu, Marianne Montemurro, Nathalie Vanzo, Michèle Crozatier -
Unveiling the structural spectrum of SARS-CoV-2 fusion by in situ cryo-ET Nat. Commun. (IF 14.7) Pub Date : 2025-06-03
Caner Akıl, Jialu Xu, Juan Shen, Peijun Zhang -
Increased antioxidative defense and reduced advanced glycation end-product formation by metabolic adaptation in non-small-cell-lung-cancer patients Nat. Commun. (IF 14.7) Pub Date : 2025-06-03
Tamara Tomin, Sophie Elisabeth Honeder, Laura Liesinger, Daniela Gremel, Bernhard Retzl, Joerg Lindenmann, Luka Brcic, Matthias Schittmayer, Ruth Birner-Gruenberger -
Inhibition of tumor-intrinsic NAT10 enhances antitumor immunity by triggering type I interferon response via MYC/CDK2/DNMT1 pathway Nat. Commun. (IF 14.7) Pub Date : 2025-06-03
Wan-cheng Liu, Yi-hong Wei, Jin-feng Chen, Xiang-ling Xing, He-xiao Jia, Xin-yu Yang, Ying-jian Huang, Xiao-min Liu, Ke Xiao, Xiao-dong Guo, Can Can, A-min Zhang, Na He, Hai-lei Zhang, Dao-xin Ma -
Sequential emergence and contraction of epithelial subtypes in the prenatal human choroid plexus revealed by a stem cell model Nat. Commun. (IF 14.7) Pub Date : 2025-06-03
Haley Masters, Shuxiong Wang, Christina Tu, Quy Nguyen, Yutong Sha, Matthew K. Karikomi, Pamela Shi Ru Fung, Benjamin Tran, Cristina Martel, Nellie Kwang, Michael Neel, Olga G. Jaime, Victoria Espericueta, Brett A. Johnson, Kai Kessenbrock, Qing Nie, Edwin S. Monuki -
Sex-specific lipidomic signatures in aortic valve disease reflect differential fibro-calcific progression Nat. Commun. (IF 14.7) Pub Date : 2025-06-03
Patricia Prabutzki, Michele Wölk, Julia Böttner, Zhixu Ni, Sarah Werner, Holger Thiele, Jürgen Schiller, Petra Büttner, Florian Schlotter, Maria Fedorova -
Science-integrity project will root out bad medical papers ‘and tell everyone’ Nature (IF 50.5) Pub Date : 2025-06-04
Group behind Retraction Watch aims to pinpoint the most influential flawed health data.
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Genomics pioneer fired from firm he founded: ‘It was not easy to domesticate me’ Nature (IF 50.5) Pub Date : 2025-06-04
Kári Stefánsson, who last month left the Icelandic genetics company deCODE, spoke to Nature about his legacy.
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Why we should protect the high seas from all extraction, forever Nature (IF 50.5) Pub Date : 2025-06-04
Callum M. Roberts, Emilia Dyer, Sylvia A. Earle, Andrew Forrest, Julie P. Hawkins, Ove Hoegh-Guldberg, Jessica J. Meeuwig, Daniel Pauly, Stuart L. Pimm, U. Rashid Sumaila, Johan Rockström, Mark LynasExploitation of the high seas risks doing irreversible damage to biodiversity, climate stability and ocean equity. A consensus must be built now to save them.
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How a mysterious epidemic of kidney disease is killing thousands of young men Nature (IF 50.5) Pub Date : 2025-06-04
Repeated damage from extreme heat over time seems to be a leading factor causing kidneys to fail.
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‘You’re just not welcome’: researchers grapple with US plan to revoke Chinese student visas Nature (IF 50.5) Pub Date : 2025-06-03
Scientists are eyeing their legal options in anticipation of new immigration actions.
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Daily briefing: NIH foreign-grant cuts could leave thousands without care worldwide Nature (IF 50.5) Pub Date : 2025-06-03
Cuts to US ‘foreign subawards’ will abruptly end hundreds of clinical trials abroad. Plus, an mpox outbreak is overwhelming Sierra Leone’s health system and a rock with a painted dot that just might represent a nose.