Group behind Retraction Watch aims to pinpoint the most influential flawed health data.

A brief encounter.

Kári Stefánsson, who last month left the Icelandic genetics company deCODE, spoke to Nature about his legacy.

Exploitation of the high seas risks doing irreversible damage to biodiversity, climate stability and ocean equity. A consensus must be built now to save them.

Repeated damage from extreme heat over time seems to be a leading factor causing kidneys to fail.

Scientists are eyeing their legal options in anticipation of new immigration actions.

Cuts to US ‘foreign subawards’ will abruptly end hundreds of clinical trials abroad. Plus, an mpox outbreak is overwhelming Sierra Leone’s health system and a rock with a painted dot that just might represent a nose.

Snippets from Nature’s past.

Letter to the Editor

Letter to the Editor

Letter to the Editor

Governments and institutions must shift from top-down approaches to collaborations with local communities.

Bot-made art undermines research and public trust in science, say illustrators frustrated by inaccurate and outlandish depictions.

Live-animal markets are a natural laboratory for viruses to evolve and spark deadly outbreaks, yet scientists lack support to study the risks they pose.

Delegates to a United Nations meeting on neurotechnology ethics have devised the first set of global guidelines on maintaining users’ privacy.

A clinical trial of CAR T cells is among the first to show that the treatment can work for solid tumours. Plus, humpbacks’ big eyes are nearsighted and how researchers are turbocharging ginseng.

Correction to: Nature https://doi.org/10.1038/s41586-025-08844-z Published online 9 April 2025

Correction to: Nature https://doi.org/10.1038/s41586-025-08630-x Published online 20 January 2025

Gaslighting is a form of psychological manipulation that, over time, causes a victim to doubt their sense of reality, often leading to a loss of agency and emotional and mental instability. Currently, mechanistic explanations for gaslighting are rooted in unfalsifiable psychodynamic theory. We propose a theoretical framework that draws upon prediction error minimization, symbolic interactionism, attachment

Plant scientist Johan Sukweenadhi uses ‘hairy-root culture’ to improve ginseng yields at the University of Surabaya in Indonesia.

Trial in China is one of the first times the immune therapy has worked against solid tumours.

Automated programs gathering training data for artificial-intelligence tools are overwhelming academic websites.

The poles hold 70% of Earth’s fresh water and are crucial to science; what’s unfolding there as the planet warms deserves greater attention.

Academia relies on unpaid labour — but researchers should think carefully about what kind of work they’re willing to give to for-profit organizations for free, says Dritjon Gruda.

A computer scientist is struggling to trust their postdoctoral research adviser after negative experiences with the previous two. How do you find one that’s right for you?

The Artemis programme and others aim to send humans to the Moon and, eventually, to Mars. Innovations in health care that support the mission crew could also benefit people at home.

How the smells of outer space could lead us to extraterrestrial life. Plus, an ancient ‘ambidextrous’ protein that can function in both mirror-image forms and the month’s best science images.

A genome-wide association study (GWAS) tests whether each of several million sites in the human genome is correlated with a trait of interest. For a number of reasons, including replication of GWAS results within families, we can be confident that significant correlations reflect in part the causal effects of DNA-level variation on the studied trait. This level of causal inference, much stronger than

US agency’s new policy could abruptly end studies of infectious diseases and cancer, leaving researchers scrambling for funds.

Freeze–thaw cycles in an icy pond could let an enzyme copy RNA double helices indefinitely — suggesting one way in which evolution could have begun.

In warming coastal seas, a crucial ecosystem is being replaced by ‘turfs’ of red algae, which release chemicals that suppress kelp survival.

Letter to the Editor

Listen to an audio version of a recent Nature Feature.

Mutation in an enzyme leads to resistance to chronic and acute pain, according to research in mice.

A concerted effort is needed to support women in their choice of journal when submitting their manuscript.

Seasoned negotiators share tips on how to handle conversations around pay, bonuses, benefits and contract length.

Modelling liver disease requires in vitro systems that replicate disease progression1,2. Current tissue-derived organoids fail to reproduce the complex cellular composition and tissue architecture observed in vivo3. Here, we describe a multicellular organoid system composed of adult hepatocytes, cholangiocytes and mesenchymal cells that recapitulates the architecture of the liver periportal region

Temporary device records eye movement and brain activity to monitor mental strain.

Reducing the number of copies of one gene in the pathogen could also make it more transmissible.

Specialized immune cells in mice can act as ‘spies’ that help the brain control behaviours such as pursuit of food. Plus, publishing outside of your research field comes with a ‘pivot penalty’ and AI tools that can ‘hear’ signs of illness in a person’s voice.

Hundreds of activists wearing gas masks took to the streets to call out their government for slashing science funding.

Most proteins are left-handed, but scientists have found an ancient molecule that works in both mirror-image forms.

Vaccines are an important tool for preventing serious illness and avoiding deaths. Vaccine hesitancy, the delay or refusal of vaccines when available or offered, is one of the top 10 threats to global public health. The acceptance and uptake, delay, or refusal of vaccines has direct health implications for individuals, their close contacts, and indirectly for others in their environment and wider social

Intelligent machine vision could get a boost from unconventional hardware design.

The COVID-19 pandemic showed the value of changing direction in research. It should be incentivized, encouraged and celebrated.

Electrochemistry is undergoing a resurgence in synthetic chemistry and boasts compelling advantages1. Repurposing natural enzymes through synthetic chemical strategies holds significant promise for exploring new chemical space2-6. Elegant strategies, including directed evolution7-10, artificial enzymes11, and photoenzymatic catalysis12,13 have demonstrated their capacities for expanding the applications

Bacteria defend themselves from viral predation using diverse immune systems, many of which target foreign DNA for degradation1. Defense-associated reverse transcriptase (DRT) systems provide an intriguing counterpoint to this strategy by leveraging DNA synthesis instead2,3. We and others recently showed that DRT2 systems use an RNA template to assemble a de novo gene that encodes an antiviral effector

The shale gas revolution has shifted propylene production from naphtha cracking to on-purpose production with propane dehydrogenation (PDH) as the dominant technology1-9. Because PDH is endothermic and requires high temperatures that favour sintering and coking, the challenge is to develop active and stable catalysts1-3 that are sufficiently stable10,11. Zeolite-supported Pt-Sn catalysts have been

Hear the biggest stories from the world of science | 28 May 2025